The case-fatality rate of hantavirus disease depends strongly on the causative hantavirus, ranging from 0.1% to 40%. However, the pathogenesis is not fully understood, and at present no licensed therapies exist. We describe fatal cases caused by Puumala hantavirus indicating involvement of complement activation and vascular leakage.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726462 | PMC |
| http://dx.doi.org/10.1093/ofid/ofx229 | DOI Listing |
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