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Clear cell hidradenoma of the male breast: A case report and literature review.

Int J Surg Case Rep

January 2025

Department of Pathology, The First Affiliated Hospital of Zhejiang University School of Medicine, No.79 Qingchun Road, Hangzhou, Zhejiang 310003, China. Electronic address:

Introduction: Clear cell hidradenoma (CCH) is a rare type of benign breast tumor that may undergo malignant transformation in a few cases. It clinically manifests as a painless breast mass, and may include nipple discharge. Complete surgical excision with adequate safety margins is the primary treatment.

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Objective: Clear cell odontogenic carcinoma (CCOC) is a rare malignancy of the jaw, presenting significant diagnostic challenges. This report aims to highlight the complexities associated with biopsy-based diagnoses of oral and maxillofacial lesions, as demonstrated in a case of intraosseous mandibular CCOC initially suggestive of Ewing's sarcoma due to its presentation with small round blue cells.

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Glycogenic acanthosis of the tongue.

Indian J Pathol Microbiol

July 2024

Department of Oral Pathology and Microbiology, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.

Glycogenic acanthosis (GA) is a benign lesion characterized by elevated, small, white plaques commonly detected in the esophageal mucosa. To date, only 6 cases have been reported in the English literature documenting its involvement in the oral cavity. Herein we report a case of large GA on the ventrolateral aspect of the tongue in a 42-year-old male (third case reported on the tongue).

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Article Synopsis
  • Gastric adenocarcinoma with enteroblastic differentiation (GAED) is a type of stomach cancer that is very serious and shows special patterns in its cells, like clear areas rich in a substance called glycogen.
  • Researchers looked at different types of gastric adenocarcinoma (like GAED and another group with enteroblastic markers) to see how aggressive they are and found that both types tend to spread more than regular gastric adenocarcinomas.
  • While GAED has a worse outcome than regular gastric adenocarcinoma, the group with enteroblastic markers has a similar chance of survival, but they are still more aggressive than the typical gastric adenocarcinoma.
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Introduction: We present a case report of excellent oncological outcome after 7-year follow up in a female Indian patient with pT2N3aM0 rare GRCC of the breast following breast conservation surgery and appropriate adjuvant treatment. Glycogen rich cell carcinoma (GRCC) is a rare subtype of primary malignant neoplasm of the breast which is not commonly discussed. Only approximately 288 cases have been reported since its first description globally with reports of varying prognosis.

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