Case: A twelve-year-old slender white girl underwent pinning of a slipped capital femoral epiphysis (SCFE) on both the right and left sides. The bilateral nature of the disease and her slender build prompted consideration of an underlying predisposition. She was referred for medical evaluation, which resulted in the identification of medullary thyroid carcinoma.
Conclusion: This report highlights the importance of recognizing atypical presentations of SCFE and the necessity for investigation of associated comorbid diagnoses. As with this case, atypical SCFE may represent the sentinel event leading to identification of underlying systemic illness and therefore may present an opportunity for early intervention.
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http://dx.doi.org/10.2106/JBJS.CC.O.00066 | DOI Listing |
Best Pract Res Clin Endocrinol Metab
January 2025
Department of Endocrinology, Seth G.S. Medical College and King Edward Memorial Hospital, Mumbai, India. Electronic address:
Adolescent primary hyperparathyroidism (PHPT) is a rare endocrine disorder bearing distinctions from the adult form. This review examines its unique aspects, focusing on clinical presentation, genetic etiologies, genotype-phenotype correlations, and therapeutic management. Adolescent PHPT often has a genetic basis, whether familial, syndromic, or apparently sporadic, and identifying the underlying genetic cause is important for patient care.
View Article and Find Full Text PDFAnim Welf
January 2025
Animal Welfare Science and Ethics Group, Department of Pathobiology and Population Sciences, Royal Veterinary College, Hawkshead Lane, Hatfield AL9 7TA, UK.
There is limited research into horse slaughter, particularly ante mortem welfare, and the effectiveness of captive-bolt gun (CBG) stunning, despite this being a widely used method worldwide. To address this evidence gap and explore associations between ante and post mortem factors, the welfare of 62 horses was assessed at a commercial Italian abattoir. Animal-based measures were used to identify stress-related behaviours and stunning effectiveness.
View Article and Find Full Text PDFJBJS Case Connect
October 2024
Palmerston North Hospital, Midcentral District Health Board, Te Whatu Ora, New Zealand.
Case: Physeal stability in slipped capital femoral epiphysis (SCFE) depends on integrity of the hypertrophic zone. This in turn is affected by imbalance between circulating growth hormones and gonadal hormones. This case describes the occurrence of SCFE in a Māori (indigenous New Zealander) transgender girl, undergoing gender-affirming therapy with a gonadal-releasing hormone analog (GnRHa).
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Orthopaedics and Trauma Surgery Faculty of Medicine, Assiut University Hospitals, Assiut, 71515, Egypt.
Background: Slipped Capital Femoral Epiphysis (SCFE) is a prevalent pediatric orthopedic condition. Treatment options range from in situ pinning to various osteotomies, with the Modified Dunn procedure gaining significant attention over the past two decades. However, the suitability of this procedure for different SCFE subtypes and the risk of avascular necrosis (AVN), particularly in moderate and severe cases, remains controversial.
View Article and Find Full Text PDFRev Bras Ortop (Sao Paulo)
December 2024
Departamento de Ortopedia Pediátrica, Hospital Infantil Joana de Gusmão, Florianópolis, SC, Brasil.
To determine whether the radiographic parameter at the epiphyseal tubercle region (peritubercle lucency sign) on the unaffected side can predict slipped capital femoral epiphysis (SCFE). We retrospectively reviewed patients who received an initial diagnosis of unilateral SCFE between 1995 and 2020 at a pediatric hospital in a Brazilian state's capital. The patients were monitored for at least 18 months.
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