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Diagnostic and prognostic performance of urine ubiquitin carboxy-terminal hydrolase L1 across multiple acute brain injury types - A longitudinal prospective cohort study.
Brain Spine
December 2024
Neurocenter, Department of Neurosurgery, Turku University Hospital and University of Turku, P.O. Box 52, FI-20521, Turku, Finland.
Introduction: Ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) is recognized as a diagnostic and prognostic blood biomarker for traumatic brain injury (TBI). This study aimed to evaluate whether UCH-L1 concentrations measured in patients' urine post-injury could serve as a diagnostic or prognostic biomarker for outcomes in various types of acute brain injuries (ABI).
Material And Methods: This pilot study included 46 ABI patients: aneurysmal subarachnoid hemorrhage (n = 22), ischemic stroke (n = 16), and traumatic brain injury (n = 8), along with three healthy controls.
Circumferential nerve wrapping with muscle autograft: a modified strategy of microvascular decompression for trigeminal neuralgia.
Neurosurg Rev
January 2025
Department of Neurosurgery, IRCCS Neuromed, Via Atinense 18, Pozzilli, IS, 86077, Italy.
Microvascular decompression is considered a first-line treatment in classical trigeminal neuralgia. Teflon is the material commonly used. The use of autologous muscle has been occasionally reported.
View Article and Find Full Text PDFGlobal Challenges in the Access of Endovascular Treatment for Acute Ischemic Stroke (Global MT Access).
Int J Stroke
January 2025
Department of Neurology, Grady memorial Hospital, Emory University, Atlanta, USA.
Background: Mechanical thrombectomy (MT) is the standard of care for eligible acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) since 2015.
Aim: Our aim was to determine the key challenges for MT implementation and access worldwide.
Methods: We conducted an international online survey consisting of 37 questions, distributed through the World Stroke Organization network, and as invited by co-authors between December 2022 and March 2023.
Editorial for "Evaluation of Neurovascular Coupling in Early-Onset and Late-Onset Epilepsy of Unknown Etiology".
J Magn Reson Imaging
January 2025
Department of Diagnostic Radiology, Singapore General Hospital, Neuroscience and Behavioural Disorders Programme, Duke-NUS Medical School, Singapore, Singapore.
Advances in Acute Ischemic and Hemorrhagic Stroke 2024.
Stroke
January 2025
Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, VIC, Australia (B.C.V.C.).
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