In many joint actions, knowledge about the precise task to be performed is distributed asymmetrically such that one person has information that another person lacks. In such situations, interpersonal coordination can be achieved if the knowledgeable person modulates basic parameters of her goal-directed actions in a way that provides relevant information to the co-actor with incomplete task knowledge. Whereas such sensorimotor communication has frequently been shown for spatial parameters like movement amplitude, little is known about how co-actors use temporal parameters of their actions to establish communication. The current study investigated whether systematic modulations of action duration provide a sufficient basis for communication. The results of 3 experiments demonstrate that knowledgeable actors spontaneously and systematically adjusted the duration of their actions to communicate task-relevant information if the naïve co-actor could not access this information in other ways. The clearer the communicative signal was the higher was the benefit for the co-actor's performance. Moreover, we provide evidence that knowledgeable actors have a preference to separate instrumental from communicative aspects of their action. Together, our findings suggest that generating and perceiving systematic deviations from the predicted duration of a goal-directed action can establish nonconventionalized forms of communication during joint action. (PsycINFO Database Record
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1037/xge0000379 | DOI Listing |
Healthcare (Basel)
December 2024
Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
The management of type 1 diabetes in pregnancy with new technologies is challenging. Sometimes the complexity of new-generation systems such as "continuous subcutaneous insulin infusion, CSII" and patient or provider preference do not allow their use, so women with type 1 diabetes in pregnancy continue to be treated with subcutaneous multiple-injection insulin therapy using pens. Smart insulin pens are new tools that allow for data collection on insulin dose and time of administration and have additional connectivity features.
View Article and Find Full Text PDFHeart Rhythm
January 2025
Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD, USA. Electronic address:
Background: Spontaneously occurring life threatening reentrant arrhythmias result when a propagating premature beat encounters a region with significant dispersion of refractoriness. Although localized structural tissue heterogeneities and prescribed cell functional gradients have been incorporated into computational electrophysiological models, a quantitative framework for the evolution from normal to abnormal behavior that occurs via disease is lacking.
Objective: The purpose of this study was to develop a probabilistic modeling framework that represents the complex interplay of cell function and tissue structure in health and disease which predicts the emergence of premature beats and the initiation of reentry.
Brain Dev
January 2025
Department of Neurology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Chongqing, China. Electronic address:
Background: Disease-modifying therapies can improve motor function in patients with spinal muscular atrophy (SMA), but efficacy varies between individuals. The aim was to evaluate the efficacy and safety of nusinersen treatment in children with SMA and to investigate prognostic factors.
Methods: Motor function, compound muscle action potential (CMAP), and other indicators were prospectively collected before and 14 months after nusinersen treatment.
Alzheimers Dement
December 2024
Annovis Bio, Malvern, PA, USA
Background: By inhibiting the translation of neurotoxic aggregating proteins ‐ amyloid precursor protein, tau, alpha‐synuclein etc., buntanetap restores axonal transport, lowers inflammation, and protects nerve cells from dying. Our Phase2 studies showed that buntanetap improved early AD patients ADAS‐Cog11 after a month treatment.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Shaperon Inc., Seoul, Korea, Republic of (South)
Background: Previously, we demonstrated therapeutic benefits following intraperitoneal delivery of the TGR5 agonist HY209 in 5xFAD, a transgenic mouse model of Alzheimer’s Disease (AD). Given the desirability of a more acceptable administration route for prolonged AD treatment, we assessed the efficacy of HY209 via oral delivery. This study aims to elucidate the therapeutic potential of NuCerin, an oral formulation of HY209, in the aforementioned AD model, while simultaneously identifying potential blood biomarkers indicative of NuCerin’s therapeutic action.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!