Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA; Department of Radiology, Duke University, Durham, North Carolina, USA.
Published: March 2018
AI Article Synopsis
Article Abstract
Current clinical abdominal imaging arrays are designed to maximize angular field of view rather than the extent of the coherent aperture. We illustrate, in ex vivo experiments, the use of a large effective aperture to perform high-resolution imaging, even in the presence of abdominal wall-induced acoustic clutter and aberration. Point and lesion phantom targets were imaged through a water path and through three excised cadaver abdominal walls to create different clinically relevant clutter effects with matched imaging targets. A 7.36-cm effective aperture was used to image the targets at a depth of 6.4 cm, and image quality metrics were measured over a range of aperture sizes using synthetic aperture techniques. In all three cases, although degradation compared with the control was observed, lateral resolution improved with increasing aperture size without loss of contrast. Spatial compounding of the large-aperture data drastically improved lesion detectability and produced contrast-to-noise ratio improvements of 83%-106% compared with the large coherent aperture. These studies indicate the need for the development of large arrays for high-resolution abdominal diagnostic imaging.
Singularity in a two-point complex coherence function, known as coherence vortices, represents zero visibility with a helical phase structure. In this paper, we introduce a novel technique to generate the coherence vortices of different topological charges by incoherent source transmittance with exotic structured binary pinholes. The binary pinhole structures have been realized by lithography, followed by wet etching methods.
Photoacoustics and Ultrasound Laboratory Eindhoven (PULS/e), Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, 5600 MB, The Netherlands.
Photoacoustic imaging creates light-induced ultrasonic signals to provide valuable information on internal body structures and tissue morphology non-invasively. A multi-aperture photoacoustic imaging (MP-PAI) system is an improvement over conventional photoacoustic imaging (PAI) systems in terms of resolution, contrast, and field of view. Previously, a prototype MP-PAI system was introduced based on multiple capacitive micromachined ultrasound transducers (CMUTs) with shared channels, such that each element in a CMUT shares its channel with its counterpart in other CMUTs.
This study demonstrates high volume rate bistatic 3-D vascular strain imaging, to overcome well-known challenges caused by the anisotropic resolution and contrast inherent to ultrasound imaging.
Approach. Using two synchronized 32x32 element matrix arrays (3.
In this study, we present the experimental proof of concept of the polarization-based filled-aperture coherent combination of two distinct broadband (sub-20 fs transform limited pulse duration at around 795 nm central wavelength) optical parametric chirped pulse amplification systems in free space. An average combination efficiency of 90% is demonstrated.
High-resolution X-ray imaging of noncrystalline objects is often achieved through the approach of scanning coherent diffractive imaging known as ptychography. The imaging resolution is usually limited by the scattering properties of the sample, where weak diffraction signals at the highest scattering angles compete with parasitic scattering. Here, we demonstrate that X-ray multilayer Laue lenses with a high numerical aperture (NA) can be used to create a strong reference beam that holographically boosts weak scattering from the sample over a large range of scattering angles, enabling high-resolution imaging that is tolerant of such background.
