AI Article Synopsis
- - The text discusses how poor dietary habits can lead to age-related diseases such as diabetes and heart issues, emphasizing the importance of dietary restriction and nutritional therapy in preventing these conditions.
- - Preclinical research highlights promising dietary interventions, such as high-fiber diets and caloric restriction, that could improve management of diabetes and its complications in future clinical trials.
- - The review aims to present preclinical evidence supporting dietary restrictions for diabetes management and explore new nutritional therapy ideas for future research and treatment strategies.
Article Abstract
The inappropriate dietary habits lead to the onset of age-related pathologies which include diabetes and cardiovascular ailments. Dietary restriction and nutritional therapy play an important role in the prevention of these chronic ailments. Preclinical research provides a basis for the therapeutic exploration of new dietary interventions for the clinical trials to potentiate the scientific management of diabetes and its related complications which further help in translating these nutritional improvements from bench to bedside. Within the same context, numerous therapeutically proved preclinical dietary interventions like high-fiber diet, caloric restriction, soy isoflavone-containing diets, etc., have shown the promising results for the management of diabetes and the associated complications. The focus of the present review is to highlight the various preclinical evidences of diet restriction for the management of diabetes and which will be helpful for enlightening the new ideas of nutritional therapy for future research exploration. In addition, some potential approaches are also discussed which are associated with various nutritional interventions to combat progressive diabetes and the associated disorders. Graphical abstract ᅟ.
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| http://dx.doi.org/10.1007/s00210-017-1453-5 | DOI Listing |
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