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Exploring the wound healing potential of dietary nitrate in diabetic rat model.
Front Physiol
November 2024
Department of Oral and Maxillofacial Surgery, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Article Synopsis
- In diabetes, wound healing is impaired due to inflammation, oxidative stress, and issues with blood vessel formation caused by high glucose levels, making treatment challenging.
- The study utilized a diabetic rat model to investigate the effects of dietary nitrate on wound healing, with various groups treated differently, including a control group and groups receiving nitrate supplementation.
- Results showed that dietary nitrate sped up wound healing by enhancing blood flow, promoting new blood vessel formation, and also had beneficial effects on glucose metabolism and inflammation, suggesting its potential use in treating wounds in diabetic patients.
Recent Progress in the Electrochemical Formation of C-N Bonds for Construction of Organic Compounds via the Use of NO/NO.
ChemSusChem
October 2024
Department of Chemical Engineering, Institute of Chemistry and Chemical Engineering, Guizhou University, Guiyang, Guizhou 550025, China.
Emissions of nitrogen oxide (NO) species (NO and NO) and nitrate/nitrite NO , such as NO and NO , have led to serious water pollution and climate challenges. How to remove these wastes is a global problem that urgently needs to be addressed. As reported, electrochemical catalytic technology under ambient conditions is of great interest for NO/NO removal.
View Article and Find Full Text PDFCurrent clinical framework on nitric oxide role in periodontal disease and blood pressure.
Clin Oral Investig
September 2024
Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health & Science, Monte da Caparica, Almada, Portugal.
Objectives: In this review, we explored potential associations between NO and its derivatives, nitrite and nitrate, with periodontal and cardiovascular diseases, with special emphasis on the former. By providing a state-of-the-art and integrative understanding of this topic, we aimed to shed light on the potential role of these three nitrogen oxides in the periodontitis-hypertension nexus, identify knowledge gaps, and point out critical aspects of the experimental methodologies.
Materials And Methods: A comprehensive literature review was conducted on human salivary and plasma concentrations of nitrate and nitrite, and their impact on periodontal and cardiovascular health.
Skeletal Muscle, Skin, and Bone as Three Major Nitrate Reservoirs in Mammals: Chemiluminescence and N-Tracer Studies in Yorkshire Pigs.
Nutrients
August 2024
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
In mammals, nitric oxide (NO) is generated either by the nitric oxide synthase (NOS) enzymes from arginine or by the reduction of nitrate to nitrite by tissue xanthine oxidoreductase (XOR) and the microbiome and further reducing nitrite to NO by XOR or several heme proteins. Previously, we reported that skeletal muscle acts as a large nitrate reservoir in mammals, and this nitrate reservoir is systemically, as well as locally, used to generate nitrite and NO. Here, we report identifying two additional nitrate storage organs-bone and skin.
View Article and Find Full Text PDFPhotodegradation of bisphenol A (BPA) in coastal aquaculture waters: Influencing factors, products, and pathways.
Chemosphere
September 2024
School of Environmental Sciences and Engineering, Qingdao University, Qingdao, 266071, PR China. Electronic address:
Bisphenol A (BPA), an endocrine-disrupting contaminant, is ubiquitous in the environment due to its presence in plastics, wastewater, and agricultural runoff. This study investigated the photodegradation behavior of BPA in coastal aquaculture waters near Qingdao, China. Lower salinity promoted BPA photodegradation, while higher salinity has an inhibitory effect, suggesting slower degradation in seawater compared to ultrapure water.
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