Introduction: Cutaneous appendageal tumor can differentiate towards or arise from either pilosebaceous apparatus or the eccrine sweat glands. Appendageal tumors are relatively rare, their clinical appearance is non-specific, and the vast majority are not diagnosed until after excision. Eccrine porocarcinoma (EP), also known as malignant eccrine poroma is a rare adnexal tumor arising from the intraepithelial ductal parts of the sweat gland.
Case Presentation: We presented a 65-year-old, Asian, female with medical co-morbids, who came with both a facial squamous cell carcinoma and a long-standing lesion over her left forearm. Histopathological finding of the left forearm demonstrated eccrine porocarcinoma.
Conclusion: Mohs micrographic surgery is the mainstay treatment of cutaneous carcinoma. It is important to rule out associated syndromes in patient who present with multiple cutaneous appendageal tumors.
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http://dx.doi.org/10.1016/j.ijscr.2017.11.066 | DOI Listing |
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
December 2024
Department of Otorhinolaryngology Head and Neck Surgery, China-Japan Friendship Hospital, Beijing100029, China.
Clin Case Rep
December 2024
Department of Dermatology Razi Hospital, Tehran University of Medical Sciences (TUMS) Tehran Iran.
Representative clinical images in this study can increase awareness regarding the clinical similarity between this benign adnexal tumor and malignant melanoma and highlight the importance of pathological examination.
View Article and Find Full Text PDFAn Bras Dermatol
December 2024
Department of Dermatology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address:
Background: Eccrine porocarcinoma (EPC) is a rare cutaneous neoplasm, commonly arising from its benign counterpart, eccrine poroma (EP), but potential unrevealed clinicopathological differences between them are not well understood.
Objectives: This study aimed to identify clinicopathological features of EP and EPC and describe the factors that may be associated with the malignant transformation of EP by comparing the two groups.
Methods: A total of 37 cases of EP and 22 cases of EPC diagnosed between January 2017 and June 2023 were retrospectively reviewed, and the clinical and histopathological characteristics were compared using statistical methods.
Diagnostics (Basel)
October 2024
Dermatology Department, Saint Pierre and Brugmann University Hospitals, Université Libre de Bruxelles, 1000 Brussels, Belgium.
Int J Dermatol
October 2024
Division of Subspecialty Medicine, Department of Medicine, Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
A 70-year-old African American female with a history of stage IV mycosis fungoides in remission presented with a gradually enlarging, red, ulcerated nodule on her right dorsal hand. The lesion was biopsied, and it showed intraepidermal proliferation with cytologic atypia and increased vasculature in the papillary dermis. Immunohistochemical staining indicated a yes-associated protein 1 (YAP1) rearrangement, confirmed by RNA sequencing, revealing a YAP1::MAML2 (mastermind-like transcriptional coactivator 2) fusion.
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