An unusual reaction is described, involving a formal intramolecular nucleophilic substitution of bromocyclopropanes with nitrogen ylides generated in situ from N-benzyl carboxamides. It is shown that this reaction involves cyclopropene intermediates and allows for the facile and expeditious preparation of 3-azabicyclo[3.1.0]hexan-2-one scaffolds.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755969 | PMC |
| http://dx.doi.org/10.1039/c7ob02068f | DOI Listing |
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