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Early Surgical Resection in Pediatric Patients with Localized Ileo-Cecal Crohn's Disease: Results of a Retrospective Multicenter Study.
J Clin Med
January 2025
Department of Medical Surgical Science and Translational Medicine, Sant' Andrea University Hospital, Sapienza University of Rome, 00185 Roma, Italy.
: Crohn's disease (CD) is an inflammatory bowel disease (IBD) that also affects pediatric patients. It frequently presents as a localized disease, affecting the ileocecal area, ileum, or colon. It requires targeted therapy to achieve a good quality of life and long-term control of disease activity.
View Article and Find Full Text PDFUtility of Protein Markers in COVID-19 Patients.
Int J Mol Sci
January 2025
Research and Innovation Unit, Hospital Costa del Sol, Autovía A-7 km 187, 29603 Marbella, Spain.
COVID-19 has been a challenge at the healthcare level not only in the early stages of the pandemic, but also in the subsequent appearance of long-term COVID-19. Several investigations have attempted to identify proteomic biomarkers in an attempt to improve clinical care, guide treatment and predict possible patient outcomes. Proteins such as C-reactive protein (CRP) or interleukin 6 (IL-6) are clear markers of severe disease, but many others have been proposed that could help in risk stratification and in the prediction of specific complications.
View Article and Find Full Text PDFThe Use of Haloperidol as a Sedative During Childbirth: An Extreme Form of Obstetric Violence in Spain.
Int J Environ Res Public Health
December 2024
European Institute of Perinatal Mental Health, Association El Parto es Nuestro (Birth is Ours), 11406 Jerez de la Frontera, Spain.
Obstetric violence during pregnancy and childbirth is unfortunately a major problem throughout the world. Neuroleptanalgesia is a classic form of analgesia which consists in administering analgesics and neuroleptics, such as haloperidol, simultaneously. Haloperidol is still occasionally used during childbirth and, in most cases, without informed consent in Spain.
View Article and Find Full Text PDFPrediction of microvascular obstruction from angio-based microvascular resistance and available clinical data in percutaneous coronary intervention: an explainable machine learning model.
Sci Rep
January 2025
Department of Cardiology, Nanjing Drum Tower Hospital, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, 210008, China.
Angio-based microvascular resistance (AMR) as a potential alternative to the index of microcirculatory resistance (IMR) and its relationship with microvascular obstruction (MVO) and other cardiac magnetic resonance (CMR) parameters still lacks comprehensive validation. This study aimed to validate the correlation between AMR and CMR-derived parameters and to construct an interpretable machine learning (ML) model, incorporating AMR and clinical data, to forecast MVO in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI). We enrolled 452 STEMI patients from Nanjing Drum Tower Hospital between 2018 and 2022, who received both PPCI and CMR.
View Article and Find Full Text PDFIMPROVEMENT OF LOWER LIMB AMPUTATION PROCEDURE IN PATIENTS WITH CRITICAL LOWER LIMB ISCHAEMIA.
Georgian Med News
November 2024
5Department of Hospital Surgery, Anesthesiology and Reanimatology, Non-Commercial Joint-Stock Company "Semey Medical University" (NCJSC «SMU»), Republic of Kazakhstan.
The relevance of the presented topic lies in the rapid growth of complications from diseases that subsequently lead to limb amputation, as well as the problem of untimely detection of ischemic tissues. The aim of the study is to determine and explain the main progressive methods of surgical treatment of obstructive diseases of vessels of different calibers that lead to circulatory disorders and tissue necrosis. The following research methods were used in the work: statistical method, bibliographic, and bibliosemantic.
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