Letter: biologics treatment in Crohn's disease and risk of bowel resection-what about the patients who stop anti-TNF therapy? Authors' reply.

Aliment Pharmacol Ther

Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

Published: January 2018

Download full-text PDF

Source
http://dx.doi.org/10.1111/apt.14398DOI Listing

Publication Analysis

Top Keywords

letter biologics
4
biologics treatment
4
treatment crohn's
4
crohn's disease
4
disease risk
4
risk bowel
4
bowel resection-what
4
resection-what patients
4
patients anti-tnf
4
anti-tnf therapy?
4

Similar Publications

Introduction: Mumps is a vaccine-preventable disease caused by the paramyxovirus affecting the salivary gland and may be complicated by orchitis, oophoritis, and encephalitis. This study aims to describe the epidemiology, clinical presentation, and transmission of mumps cases in the Kingdom of Bahrain between 2012 and 2022.

Methodology: A retrospective cross-sectional study was conducted using national surveillance data of confirmed mumps cases, including all age groups and both Bahraini and non-Bahraini nationals, from January 2012 to December 2022.

View Article and Find Full Text PDF

Environmental conditions influence the maternal deposition of hormones into eggs, which is hypothesized to adaptively modify developmental outcomes in offspring. However, most ecosystems harbour environmental contaminants capable of disrupting endocrine signaling, and maternal exposure to these compounds has the potential to further alter offspring traits. Studies rarely examine maternally derived hormones and contaminants along with offspring phenotypes, and we know little about their interrelationships and potential interactions.

View Article and Find Full Text PDF

Fibrosis in PCLS: comparing TGF-β and fibrotic cocktail.

Respir Res

January 2025

Department for Pulmonary Medicine, Allergology and Clinical Immunology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Introduction: Fibrotic cocktail (FC) is a combination of pro-fibrotic and pro-inflammatory mediators that induces early fibrotic changes in organotypic lung models. We hypothesised that transforming growth factor beta 1 (TGF-β1) alone induces a pro-fibrotic effect similar to FC. Our aim was to compare the pro-fibrotic effects of TGF-β1 with FC in human precision-cut lung slices (PCLS).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!