Prevalence of Genotypes and Gene in Dental Plaque of Asymptomatic Mexican Children.

Biomed Res Int

Posgrado de Ortodoncia, Facultad de Odontología (FO), Universidad Autónoma de Nuevo León (UANL), Av. Dr. Aguirre Pequeño 1504, Col. Mitras Centro, 64460 Monterrey, NL, Mexico.

Published: July 2018

AI Article Synopsis

  • The study investigated the link between gastrointestinal disease-related genes and the presence of certain bacteria in the mouths of Mexican children without dyspeptic symptoms.
  • Out of 100 children, 38% tested positive for a specific oral bacteria gene, with a notable connection found between oral infection and gingival health.
  • The research indicated that specific genotypes were more common in cases of gingivitis, suggesting that gastrointestinal-related bacteria in the mouth may play a role in the progression of gingivitis in asymptomatic children.

Article Abstract

The variability in and genes has been related to the progression of the gastrointestinal disease; also the presence of in the oral cavity has been associated with periodontal disease in adults, but, in children without dyspeptic symptoms, little is known about this. We evaluated the prevalence of and the presence of / genotypes in the oral cavity of Mexican children without dyspeptic symptoms. The gingival status was measured, and dental plaque samples ( = 100) were taken. 38% of children were positive for 16S rRNA gene by qPCR. A significant association between oral infection and gingival status was observed ( < 0.001). In 34.6% (9/26) of mild gingivitis cases, genotype was found, while was typed in 50% (3/6) of moderate gingivitis. The prevalence among -positive children was 80.8% (21/26), 83.3% (5/6), and 16.7% (1/6) of cases of mild gingivitis, moderate gingivitis, and nongingivitis, respectively ( < 0.001). The + combinational genotype was the most detected in children with gingivitis. Our results suggest that the prevalence of and detection of genotypes-associated gastrointestinal disease in the oral cavity could be related to the progression of gingivitis in asymptomatic children.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687131PMC
http://dx.doi.org/10.1155/2017/4923640DOI Listing

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