The variability in and genes has been related to the progression of the gastrointestinal disease; also the presence of in the oral cavity has been associated with periodontal disease in adults, but, in children without dyspeptic symptoms, little is known about this. We evaluated the prevalence of and the presence of / genotypes in the oral cavity of Mexican children without dyspeptic symptoms. The gingival status was measured, and dental plaque samples ( = 100) were taken. 38% of children were positive for 16S rRNA gene by qPCR. A significant association between oral infection and gingival status was observed ( < 0.001). In 34.6% (9/26) of mild gingivitis cases, genotype was found, while was typed in 50% (3/6) of moderate gingivitis. The prevalence among -positive children was 80.8% (21/26), 83.3% (5/6), and 16.7% (1/6) of cases of mild gingivitis, moderate gingivitis, and nongingivitis, respectively ( < 0.001). The + combinational genotype was the most detected in children with gingivitis. Our results suggest that the prevalence of and detection of genotypes-associated gastrointestinal disease in the oral cavity could be related to the progression of gingivitis in asymptomatic children.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687131 | PMC |
http://dx.doi.org/10.1155/2017/4923640 | DOI Listing |
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