IgA Vasculitis with Simultaneous Cardiopulmonary Involvement.

Intern Med

Division of Cardiology, Department of Medicine II, Kansai Medical University, Japan.

Published: March 2018

A 60-year-old man with a history of hypertension, type 2 diabetes, and reflux esophagitis was admitted to our hospital with hemoptysis, dyspnea, and leg edema. We diagnosed him with adult IgA vasculitis based on the presence of purpura, elevated serum IgA fibronectin complexes, pathophysiological findings, a skin biopsy showing leukocytoclastic vasculitis, and immunofluorescence studies demonstrating granular IgA and C3 deposits in the blood vessel wall. He showed concurrent cardiopulmonary involvement without involvement of the gastrointestinal system and kidneys, which are commonly affected in IgA vasculitis patients. Following treatment with prednisolone, the patient recovered with improvement in cardiopulmonary manifestations.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891522PMC
http://dx.doi.org/10.2169/internalmedicine.9681-17DOI Listing

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