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Expert Rater Agreement for Symptoms and Diagnosis of Bipolar Disorder in Youth.
Child Psychiatry Hum Dev
January 2025
Department of Psychiatry and Behavioral Health, Stony Brook University, 101 Nicolls Road, Stony Brook, NY, USA.
The diagnosis of bipolar disorder (BD) in young children has been a topic of debate, in part owing to varied interpretation of manic-like symptoms. We examined how expert academic clinicians participating in the pediatric bipolar biobank varied in their interpretation and application of Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria and diagnoses. Study co-investigators reviewed 12 standardized narratives and for each marked a visual analog scale with their confidence in the presence of manic episodes and criteria.
View Article and Find Full Text PDFGene Variant Related Neurological and Molecular Biomarkers Predict Psychosis Progression, with Potential for Monitoring and Prevention.
Int J Mol Sci
December 2024
Department of Psychiatry, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA 5000, Australia.
The ( C677T gene polymorphism is associated with neurological disorders and schizophrenia. Patients diagnosed with schizophrenia and schizoaffective disorder and controls ( 134) had data collected for risk factors, molecular and neuro-sensory variables, symptoms, and functional outcomes. Promising gene variant-related predictive biomarkers were identified for diagnosis by Receiver Operating Characteristics and for illness duration by linear regression.
View Article and Find Full Text PDFA Comparative Study on the Clinical Outcomes of Bipolar Radiofrequency Thermotherapy Versus Transurethral Resection of the Prostate in Storage Symptoms Associated With Benign Prostatic Obstruction.
Int Neurourol J
December 2024
Department of Urology, Lokman Hekim University, Ankara, Turkey.
Purpose: The aim of the study was to compare the results of radiofrequency (RF) thermotherapy and transurethral resection of the prostate (TURP) in patients who required benign prostatic obstruction (BPO) surgery and had storage symptoms.
Methods: The results of patients who had undergone TURP and RF thermotherapy procedures between December 2019 and 2022 were compared before and after the procedure. Patients' International Prostate Symptom Scores, maximum flow rate (Qmax), postvoiding residues, and overactive bladder validated 8 scores (OAB-V8) at 3 and 6 months were analyzed.
Addressing Perinatal Mood and Anxiety disorders in Obstetric Settings: Results of a Cluster Randomized Controlled Trial of Two Approaches.
Am J Obstet Gynecol MFM
January 2025
University of Massachusetts Chan Medical School, Department of Obstetrics and Gynecology, Psychiatry, Pediatrics, Population and Quantitative Health Sciences; UMass Memorial Health Department of Obstetrics and Gynecology(2), Worcester, MA.
Article Synopsis
- Mood and anxiety disorders affect one in five perinatal individuals, yet they are often not adequately treated due to various barriers in obstetric practices. To improve this situation, implementation assistance and an e-learning toolkit were developed for obstetric clinicians.
- The main goal was to assess how these resources impacted the screening and treatment of mood and anxiety disorders compared to usual care by conducting a cluster randomized controlled trial across 13 obstetric practices in the U.S.
- Results showed that there were no significant differences at baseline in mental health screening documentation among the groups, indicating a need for enhanced strategies in documenting and addressing these disorders effectively.
Early Onset Active Inflammatory Bowel Disease Is Associated With Psychiatric Comorbidities: A Multi-Network Propensity-Matched Cohort Study.
Crohns Colitis 360
January 2025
Digestive Health Institute, Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Background: Psychiatric disease burden in patients with Inflammatory bowel disease (IBD) has risen substantially over the past few decades. However, there is limited data on the relationship between IBD disease activity and the incidence of psychiatric comorbidities. We sought to conduct a population-based study to investigate the impact of early onset disease activity in newly diagnosed IBD patients on psychiatric disease diagnoses and medication usage.
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