Cancer Incidence Among Hardmetal Production Workers: The Swedish Cohort.

J Occup Environ Med

Department of Medical Science, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden (Dr Svartengren); Department of Occupational and Environmental Medicine, Faculty of Science, Örebro University, Örebro, Sweden (Ms Bryngelsson, Dr Westberg); Center for Occupational Biostatistics and Epidemiology, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania (Drs Marsh, Buchanich, Ms Zimmerman); and Division of Environmental and Occupational Health Sciences, School of Public Health, University of Illinois at Chicago, Chicago, Illinois (Ms Kennedy, Dr Esmen).

Published: December 2017

: The cancer incidence was determined for 3713 workers from three plants from 1958 to 2011. The exposure measures were ever/never exposed, duration, cumulative, and mean cobalt concentrations.The incidence of all malignant neoplasms was increased at one plant, but standardized incidence ratio (SIR) was 0.96 for all workers. Lung cancer incidence was increased for all workers, SIR 1.38 (1.01 to 1.85). The lung cancer incidence was associated with shorter employment time and showed no exposure-response. There was decreased incidence for skin cancer. Increased lip cancer incidence found at one of the production plants might be related to diagnostic intensity.Lung cancer incidence showed no correlation to cobalt exposure based on internal comparison. The increased SIR for all workers might be associated with other factors.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732645PMC
http://dx.doi.org/10.1097/JOM.0000000000001185DOI Listing

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