Life-Threatening Thrombocytopenia Following Intravenous Contrast Media Infusion.

Yonsei Med J

Divison of Hematology-Oncology, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.

Published: January 2018

AI Article Synopsis

  • A 63-year-old man developed severe acute thrombocytopenia after his first use of intravenous non-ionic contrast media, with no immediate allergic reactions present.
  • His platelet count plummeted from 107,000/μL to 2,000/μL within six hours after the infusion.
  • Treatment with corticosteroids and platelet transfusions successfully restored his platelet count to normal levels over five days, marking a unique case in medical documentation.

Article Abstract

Radiocontrast media-induced acute severe thrombocytopenia is a very rare complication and potentially life-threatening. Here, we report the case of a 63-year-old male patient with severe acute thrombocytopenia following first exposure to intravenous non-ionic contrast media without immediate allergic reactions. His platelet count dropped from 107000/μL to 2000/μL after six hours of radiocontrast infusion. After administration of corticosteroid and transfusion of platelet concentrates, the platelet count returned gradually to normal within 5 days. To the best of our knowledge, non-ionic contrast media-induced isolated acute severe thrombocytopenia following no signs or symptoms of immediate allergic reaction has never been described.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725355PMC
http://dx.doi.org/10.3349/ymj.2018.59.1.158DOI Listing

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