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The year 2023 marks the 80th year of publication of Annals of Allergy, Asthma & Immunology. To celebrate this important milestone, we look back on the history of the journal from its inception to the present day. This special article explores the rationale and people involved in creating the journal and highlights major advances in Annals history.

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Regional science has, in its great history since the 1950s, made a decisive contribution to a better scientific understanding of spatial development issues and dynamics and to a more effective implementation of knowledge-based regional policy in many countries of the world, in both developed and developing nations on our planet. This special issue of the annals of regional science, titled "Spotlight on the Region", celebrates the scholarly importance and impact of the late Roger Stough on regional science. The issue is comprised of fourteen self-standing on regional and urban development and highlights the critical importance of regional and urban dimensions in sustainable development.

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Dr. Vladimir Fortunato (1885-1938), once lauded but now obscure Russian-American medical model sculptor.

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Abbott Library, Robert L. Brown History of Medicine Collection, University at Buffalo, Buffalo, NY, USA.

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'The Apportionment of Human Diversity' stands as a noteworthy intervention, both for the field of human population genetics as well as in the annals of public communication of science. Despite the widespread uptake of Lewontin's conclusion that racial classification is of 'virtually no genetic or taxonomic significance', the biomedical research community continues to grapple with whether and how best to account for race in its work. Nowhere is this struggle more apparent than in the latest attempts to translate genetic associations with complex disease risk to clinical use in the form of polygenic risk scores, or PRS.

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