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Findings from an expert focus group on psychotropic medication deprescribing practices for children and youth with complex needs.
Front Child Adolesc Psychiatry
November 2024
Applied Research & Evaluation, Child and Parent Resource Institute, Ministry of Children, Community and Social Services, London, ON, Canada.
Introduction: Psychotropic medication can be effective at stabilizing emotional and behavioural disturbances associated with physiological processes in children and youth. When medication benefits, indication or adverse effects are queried, deprescribing should be considered. Current guidelines for deprescribing are mainly for adults/elderly and largely theoretical, not practical, especially for polypharmacy.
View Article and Find Full Text PDFA novel adaptive lightweight multimodal efficient feature inference network ALME-FIN for EEG emotion recognition.
Cogn Neurodyn
December 2025
School of Mechatronical Engineering, Beijing Institute of Technology, No. 5 Zhongguancun South Street, Haidian District, Beijing, 100081 China.
Enhancing the accuracy of emotion recognition models through multimodal learning is a common approach. However, challenges such as insufficient modal feature learning in multimodal inference and scarcity of sample data continue to pose obstacles that need to be overcome. Therefore, we propose a novel adaptive lightweight multimodal efficient feature inference network (ALME-FIN).
View Article and Find Full Text PDFWe demonstrate a (FMCW) light detection and ranging (LIDAR) system utilizing a (SNSPD) to measure vibrational spectra using reflected signals at the single-photon level. By determining the time-variant Doppler shift of the reflected probe signal, this system successfully reconstructs various audio signals, including pure sinusoidal, multi-tonal, and musical signals, up to 200 Hz, limited by the laser frequency modulation rate and the Nyquist sampling theorem. Additionally, we employ scanning galvo mirrors to perform 3D measurements and map audio signals from different regions in the scanned field of view.
View Article and Find Full Text PDFLiver transplantation for homozygous familial hypercholesterolemia: a retrospective analysis from Chinese experience.
Orphanet J Rare Dis
January 2025
Department of Critical Liver Diseases, Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Background: Homozygous familial hypercholesterolaemia (HoFH) increases risk of premature cardiovascular events and cardiac death. In severe cases of HoFH, clinical signs and symptoms cannot be controlled well by non-surgical treatments, liver transplantation (LT) currently represents the viable option.
Method: To assess the clinical efficacy, prognosis, and optimal timing of LT for HoFH, a retrospective analysis was conducted on the preoperative, surgical conditions, and postoperative follow-up of children who received an LT for HoFH at the Beijing Friendship Hospital over the period from December 2014 to August 2022.
Syntalos: a software for precise synchronization of simultaneous multi-modal data acquisition and closed-loop interventions.
Nat Commun
January 2025
Institute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University, Heidelberg, Germany.
Complex experimental protocols often require multi-modal data acquisition with precisely aligned timing, as well as state- and behavior-dependent interventions. Tailored solutions are mostly restricted to individual experimental setups and lack flexibility and interoperability. We present an open-source, Linux-based integrated software solution, called 'Syntalos', for simultaneous acquisition and synchronization of data from an arbitrary number of sources, including multi-channel electrophysiological recordings and different live imaging devices, as well as closed-loop, real-time interventions with different actuators.
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