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http://dx.doi.org/10.1136/thoraxjnl-2017-210866 | DOI Listing |
FASEB J
January 2025
Laboratory of Tissue Biology and Therapeutic Engineering, UMR5305 CNRS, University Lyon 1, Lyon Cedex 07, France.
G-Protein Coupled Receptor, Class C, Group 5, Member A (GPRC5A) has been extensively studied in lung and various epithelial cancers. Nevertheless, its role in the skin remains to be elucidated. In this study, we sought to investigate the function of this receptor in skin biology.
View Article and Find Full Text PDFDalton Trans
January 2025
Graduate School of Science and Technology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571, Japan.
The reactions of the sterically demanding ferrocenyl lithium dimer (Fc*Li) (Fc* = 2,5-bis(3,5-di--butyl-phenyl)-1-ferrocenyl) with aluminum trihalides (AlCl, AlBr, and AlI) to furnish the corresponding monomeric bis(ferrocenyl)haloalumanes are reported. In the case of the reaction with AlI, an unexpected intramolecular 1,1'-aluminum migration in the ferrocenyl moiety was found to occur. Their monomeric structures with a tri-coordinated aluminum atom show affinitive Al⋯Fe interactions.
View Article and Find Full Text PDFNat Cell Biol
January 2025
State Key laboratory of Genetic Engineering, School of Life Sciences, Liver Cancer Institute of Zhongshan Hospital, Fudan University, Shanghai, China.
Severe damage to the intrahepatic biliary duct (IHBD) network occurs in multiple human advanced cholangiopathies, such as primary sclerosing cholangitis, biliary atresia and end-stage primary biliary cholangitis. Whether and how a severely damaged IHBD network could reconstruct has remained unclear. Here we show that, although the gallbladder is not directly connected to the IHBD, there is a common hepatic duct (CHD) in between, and severe damage to the IHBD network induces migration of gallbladder smooth muscle cells (SMCs) to coat the CHD in mouse and zebrafish models.
View Article and Find Full Text PDFDisappointment is a vital factor in the learning and adjustment of strategies in reward-seeking behaviors. It helps them conserve energy in environments where rewards are scarce, while also increasing their chances of maximizing rewards by prompting them to escape to environments where richer rewards are anticipated (e.g.
View Article and Find Full Text PDFOphthalmol Sci
November 2024
Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Purpose: Autologous retinal transplantation has been successfully employed in the treatment of large and myopic macular holes that are refractory to standard surgical treatments. Patients transplanted with a peripheral neurosensory retinal graft have shown unexpected improvements in visual acuity. The study aims to investigate if neural integration of the graft takes place in a porcine model of retinal hole.
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