Advanced informatics systems can help improve health care delivery and the environment of care for critically ill patients. However, identifying, testing, and deploying advanced informatics systems can be quite challenging. These processes often require involvement from a collaborative group of health care professionals of varied disciplines with knowledge of the complexities related to designing the modern and "smart" intensive care unit (ICU). In this article, we explore the connectivity environment within the ICU, middleware technologies to address a host of patient care initiatives, and the core informatics concepts necessary for both the design and implementation of advanced informatics systems.
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http://dx.doi.org/10.1097/CNQ.0000000000000186 | DOI Listing |
Alzheimers Dement
December 2024
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Background: Black Americans (BAs), Hispanics/Latinos (H/Ls), and Africans (As) face a disproportionate burden of aging and Alzheimer's Disease and Related Dementias (AD/ADRD), coupled with underrepresentation in research. Further, researchers also report a lack of compliance on sensitive social determinants of health data for AD/ADRD research. For instance, the PRAPARE tool reports a low completion rate in community and clinical settings.
View Article and Find Full Text PDFBackground: Assistive technology (AT) plays a crucial role in empowering people living with dementia (PLWD) to perform tasks independently, enhancing their autonomy and dignity. To build on this foundation, our proposal introduces a home-based reminder system designed to further support PLWD in their daily lives.
Hypothesis: Memory aid technology, in particular reminder systems, can be developed to prospectively provide PLWD with autonomy and independence, to alleviate responsibilities and time commitments of caregivers and clinicians, and to enable remote behavioral monitoring.
Alzheimers Dement
December 2024
Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.
"Dual Perspectives" integrates multiple MRI scans, creating a nuanced synthesis of grey matter and diffusion-based regional connections. This rendering holds particular significance in the realm of Alzheimer's and dementia research by offering a comprehensive examination of data crucial for understanding these complex neurodegenerative conditions. The inclusion of grey matter provides a detailed insight into the structural composition of the brain.
View Article and Find Full Text PDFSAGE Open Med Case Rep
January 2025
PhD in Health Science Program, Faculty of Medicine, Mahasarakham University, Mahasarakham, Thailand.
This case report emphasizes the complexities involved in dental implant placement within the anterior esthetic zone, focusing on the integration of advanced surgical techniques and meticulous prosthetic design for optimal esthetic and functional results. A 28-year-old male presented with the absence of the upper left central incisor, which had been extracted 5 years prior due to fracture. Clinical and radiographic assessments indicated normal alveolar bone levels; however, the esthetic demands required a specialized approach.
View Article and Find Full Text PDFBrief Bioinform
November 2024
IBM Research Europe, Säumerstrasse 4, CH-8803 Rüschlikon, Switzerland.
Enzymes are molecular machines optimized by nature to allow otherwise impossible chemical processes to occur. Their design is a challenging task due to the complexity of the protein space and the intricate relationships between sequence, structure, and function. Recently, large language models (LLMs) have emerged as powerful tools for modeling and analyzing biological sequences, but their application to protein design is limited by the high cardinality of the protein space.
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