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Similar Publications

Mechanical and optical properties of additively manufactured denture base resin in different colors modified with antimicrobial substances: An in vitro study.

J Prosthet Dent

January 2025

Associate Professor, Department of Restorative, Preventive and Pediatric Dentistry, School of Dental Medicine, University of Bern, Switzerland; and Adjunct Professor, Division of Restorative and Prosthetic Dentistry, The Ohio State University, Columbus, OH.

Statement Of Problem: Acrylic denture base resins are subject to colonization by oral and nonoral bacteria, contributing to the onset of denture stomatitis. However, how the addition of antimicrobial substances affects the mechanical and optical properties of additively manufactured denture base resin remains unclear.

Purpose: The purpose of this in vitro study was to investigate the surface roughness, color stainability, and flexural strength of antimicrobial-modified, additively manufactured polymethyl methacrylate (PMMA) denture base resin in tooth and gingiva colors.

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Statement Of Problem: Denture stomatitis (DS) is a common oral disorder in patients with complete maxillary dentures. Typical treatments such as nystatin or azoles lead to drug resistance after a long period. Several studies have shown the antifungal activity of statins against Candida albicans; however, studies on the antifungal effect of atorvastatin against DS are lacking.

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Causal effects of circulating inflammatory proteins on oral phenotypes: Deciphering immune-mediated profiles in the host-oral axis.

Int Immunopharmacol

January 2025

Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, 166th Qiutao Road, Hangzhou, 310000, China.. Electronic address:

Article Synopsis
  • Oral health can indicate larger health issues, with inflammatory proteins playing a key role in linking oral and systemic health.
  • A study used genetic data to analyze the causal effects of 91 inflammatory proteins on 17 oral traits, identifying 5 proteins that significantly correlated with specific oral conditions.
  • These findings enhance our understanding of how immune responses are linked to oral health and could inform future clinical practices and public health strategies.
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Antimicrobial role of Lavandula angustifolia towards Candida albicans, Streptococcus mutans, Staphylococcus aureus and anti-adherence effect on denture base resin.

J Oral Biol Craniofac Res

November 2024

Department of Oral Pathology, SRM Institute of Science and Technology, SRM dental college, Ramapuram campus, Chennai, TamilNadu, India, 600089.

Objectives: The objective of the study was to determine the antimicrobial efficacy of Lavandula angustifolia (True Lavender extract) towards Candida albicans, Streptococcus mutans, Staphylococcus aureus pathogens. Varying proportions of the extract was incorporated into polymethyl methacrylate (PMMA) denture base resin and the anti-adherent effect was investigated.

Methods: An in-vitro study was performed after pure extract was obtained from Lavandula angustifolia (LA) flowers using a solvent based hot extraction process.

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Article Synopsis
  • The study investigates the use of natural products as disinfectants for PMMA dentures, focusing on their potential to prevent denture stomatitis in wearers.
  • After reviewing literature, 46 studies were selected that assessed 39 different natural products for their effectiveness against Candida albicans, with 43 showing positive results.
  • The findings indicate that while natural products, especially those from plants, are promising in lab settings, more clinical research is needed to confirm their effectiveness in real-world scenarios involving denture users.
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