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Factors affecting mass inflow of quaternary ammonium compounds into Japanese sewage treatment plants.
J Environ Manage
December 2024
Botanical Garden, Institute of Nature and Environmental Technology, Kanazawa University, Kakumamachi, Kanazawa, Ishikawa, 920-1192, Japan.
Quaternary ammonium compounds (QACs), ecotoxic organic chemicals linked to multidrug resistance, are being used increasingly, for example to prevent the transmission of infections such as covid-19, in households, hospitals, and industry. To understand the locations, fluctuations, and fractions of QACs entering sewers, we monitored 14 QACs (benzalkonium chloride [BAC]-C8, C10, C12, C14, C16, and C18; dialkyldimethylammonium chloride [DDAC]-C8, C10, and C12; alkyltrimethylammonium chloride [ATAC]-C12, C16, and C18; benzethonium chloride; and cetylpyridinium chloride), and a disinfectant (chlorhexidine) in influent at four Japanese sewage treatment plants (STPs) five times throughout a year. Mass inflows were relatively stable throughout the year, indicating that the recent seasonal covid-19 epidemic did not greatly influence them.
View Article and Find Full Text PDFComparative assessment of microbiome and resistome of influent and effluent of sewage treatment plant and common effluent treatment plant located in Delhi, India using shotgun approach.
J Environ Manage
October 2024
Department of Microbiology, Ram Lal Anand College, University of Delhi, South Campus, New Delhi, 110021, India. Electronic address:
Antimicrobial resistance (AMR) is a significant threat that demands surveillance to identify and analyze trends of the emerging antibiotic resistance genes (ARGs) and potential microbial carriers. The influent of the wastewater treatment plants (WWTPs) reflects the microbes derived from the population and effluent being the source of dissemination of potential pathogenic microbes and AMR. The present study aimed to monitor microbial communities and antibiotic resistance genes in WWTPs employing a whole metagenome shotgun sequencing approach.
View Article and Find Full Text PDFMicrobial community and functions involved in smokeless tobacco product: a metagenomic approach.
Appl Microbiol Biotechnol
June 2024
Division of Molecular Genetics and Biochemistry, Molecular Biology Group, ICMR-National Institute of Cancer Prevention and Research, Noida, India.
Smokeless tobacco products (STPs) are attributed to oral cancer and oral pathologies in their users. STP-associated cancer induction is driven by carcinogenic compounds including tobacco-specific nitrosamines (TSNAs). The TSNAs synthesis could enhanced due to the metabolic activity (nitrate metabolism) of the microbial populations residing in STPs, but identifying microbial functions linked to the TSNAs synthesis remains unexplored.
View Article and Find Full Text PDFA decision support system for localized planning of reclaimed water around wastewater treatment plants.
Environ Sci Pollut Res Int
May 2024
Department of Civil Engineering, Indian Institute of Technology, Banaras Hindu University, Varanasi, Uttar Pradesh, 226010, India.
Exploding population, industrialization, and an increase in water pollution has led to acute shrinkage in freshwater availability. Numerous countries have started exploring municipal wastewater as a new potential source of water to bring a paradigm shift from linearity to obtaining circularity in human water cycle management. This study aims to develop a decision support system for integrated water and wastewater management (DSS_IWWM), targeted towards reuse-focused selection of appropriate wastewater treatment technology, and localized planning around STPs in terms of reclaimed water demand identification, estimation, allocation, and sustainable pricing.
View Article and Find Full Text PDFPhenotype-guided targeted therapy based on functional signal transduction pathway activity in recurrent ovarian cancer patients: The STAPOVER study protocol.
Heliyon
January 2024
Department of Obstetrics and Gynaecology and Catharina Cancer Institute, Catharina Hospital, Eindhoven, the Netherlands.
Objective: Ovarian cancer is the fifth cause of cancer-related death among women. The benefit of targeted therapy for ovarian cancer patients is limited even if treatment is stratified by molecular signature. There remains a high unmet need for alternative diagnostics that better predict targeted therapy, as current diagnostics are generally inaccurate predictors.
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