A review on the antagonist Ebola: A prophylactic approach.

Biomed Pharmacother

Computational Intelligence and Bioinformatics Lab, Department of Computer Science, Jamia Millia Islamia, New Delhi, 110025, India. Electronic address:

Published: December 2017

AI Article Synopsis

  • Ebola virus (EBOV) is a severe threat to human health, causing Ebola Virus Disease (EVD), characterized by severe hemorrhagic fever and significant loss of life during outbreaks.
  • Research on EBOV has intensified, focusing on its interaction with the immune system, which is crucial for understanding the virus's behavior and developing effective therapies.
  • The article reviews various aspects of Ebola research, including symptoms, transmission, antiviral development, health system resilience, and future challenges and opportunities in the field.

Article Abstract

Ebola virus (EBOV), a member of Filoviridae virus family under the genus Ebolavirus, has emerged as a dangerous and potential threat to human health globally. It causes a severe and deadly hemorrhagic fever in humans and other mammals, called Ebola Virus Disease (EVD). In recent outbreaks of EVD, there has been loss of large numbers of individual's life. Therefore, EBOV has attracted researchers and increased interests in developing new models for virus evolution, and therapies. The EBOV interacts with the immune system of the host which led to understand how the virus functions and effects immune system behaviour. This article presents an exhaustive review on Ebola research which includes EVD illness, symptoms, transmission patterns, patho-physiology conditions, development of antiviral agents and vaccines, resilient health system, dynamics and mathematical model of EBOV, challenges and prospects for future studies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126370PMC
http://dx.doi.org/10.1016/j.biopha.2017.11.103DOI Listing

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