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A STEMI Complicated by Cardiogenic Shock Due to Simultaneous Acute Thrombosis of Two Coronary Vessels in the 'Deadly Double Infarct Syndrome': A Case Report and Discussion of Literature.
J Clin Med
December 2024
Department of Biomedical and Clinical Sciences, University of Milan, 20122 Milan, Italy.
: ST-segment elevation myocardial infarction (STEMI) remains a leading cause of mortality worldwide, primarily caused by acute thrombosis over atherosclerotic plaques. Simultaneous acute thrombosis in two coronary arteries is an exceptionally rare event. This report highlights a unique case of STEMI associated with cardiogenic shock due to dual coronary artery thrombosis and provides insights from a literature review on this rare condition.
View Article and Find Full Text PDFThe progress of drug targets.
Front Med (Lausanne)
October 2024
Qingdao Chest Hospital, Qingdao, Shandong, China.
Tuberculosis (TB) has been troubling humans for hundreds of years, is a highly infectious disease caused by (Mtb) infection, Mtb can infect almost all organs of the body and is one of the deadly infectious diseases in the world. At present, the first-line treatment regimen has a long treatment cycle and is prone to multiple drug resistance. Anti-tuberculosis drugs and latent tuberculosis infection (LTBI) resistance are increasing year by year, and new targets and new bioactive compounds are urgently needed to treat this disease.
View Article and Find Full Text PDFA Case Report of Methicillin-Resistant Staphylococcus aureus-Related Pericardial Empyema: A Deadly Cardiac Risk.
Cureus
October 2024
Internal Medicine, Nuvance Health, Poughkeepsie, USA.
Article Synopsis
- Pericardial empyema is a rare but serious condition, typically discovered after death, often caused by Staphylococcus aureus, especially MRSA.
- A 73-year-old man with diabetes and hypothyroidism showed symptoms like fever and skin infection, leading to the discovery of MRSA and treatment with Vancomycin.
- Despite emergency procedures, the patient developed severe complications, resulting in his death, highlighting the importance of quick diagnosis and treatment for better outcomes.
Concordance of Chest Radiography and Chest Computed Tomography Findings in Patients with Hematologic Malignancy and Invasive Mucormycosis: What Are the Prognostic Implications?
J Fungi (Basel)
October 2024
Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Invasive pulmonary mucormycosis (IPM) is a deadly opportunistic mold infection in patients with hematological malignancies (HM). Radiologic imaging is essential for its timely diagnosis. Here, we compared IPM lesions visualized by chest computed tomography (CCT) and chest X-ray (CXR) and determined the prognostic significance of discordant imaging.
View Article and Find Full Text PDFTargeted and cytotoxic inhibitors used in the treatment of lung cancers.
Pharmacol Res
November 2024
Blue Ridge Institute for Medical Research, 221 Haywood Knolls Drive, Hendersonville, NC 28791, United States. Electronic address:
Article Synopsis
- * Stage I/II NSCLC is typically treated with surgery, while other treatments like chemoradiotherapy, immune checkpoint inhibitors, and specific targeted therapies are available for various mutations present in NSCLC cases.
- * SCLC, representing about 15% of lung cancer, has a poor prognosis; treatment for extensive-stage SCLC involves a combination of platinum-based chemotherapy and anti-PDL1 inhibitors.
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