AI Article Synopsis
- Stomach cancer was once a leading cause of cancer deaths in the U.S. but has declined over the past century, although it still significantly affects specific populations like blacks, Asians, and Native Americans.
- A study analyzed survival rates for stomach cancer patients across various states, revealing a slight increase in 5-year survival rates from 26.1% to 29% between two time periods (2001-2003 and 2004-2009), with no racial differences found in outcomes.
- Despite improvements, stomach cancer remains deadly, particularly shortly after diagnosis, highlighting the need for better prevention strategies by addressing known risk factors.
Article Abstract
Background: Stomach cancer was a leading cause of cancer-related deaths early in the 20th century and has steadily declined over the last century in the United States. Although incidence and death rates are now low, stomach cancer remains an important cause of morbidity and mortality in black, Asian and Pacific Islander, and American Indian/Alaska Native populations.
Methods: Data from the CONCORD-2 study were used to analyze stomach cancer survival among males and females aged 15 to 99 years who were diagnosed in 37 states covering 80% of the US population. Survival analyses were corrected for background mortality using state-specific and race-specific (white and black) life tables and age-standardized using the International Cancer Survival Standard weights. Net survival is presented up to 5 years after diagnosis by race (all, black, and white) for 2001 through 2003 and 2004 through 2009 to account for changes in collecting Surveillance, Epidemiology, and End Results Summary Stage 2000 data from 2004.
Results: Almost one-third of stomach cancers were diagnosed at a distant stage among both whites and blacks. Age-standardized 5-year net survival increased between 2001 to 2003 and 2004 to 2009 (26.1% and 29%, respectively), and no differences were observed by race. The 1-year, 3-year, and 5-year survival estimates were 53.1%, 33.8%, and 29%, respectively. Survival improved in most states. Survival by stage was 64% (local), 28.2% (regional), and 5.3% (distant).
Conclusions: The current results indicate high fatality for stomach cancer, especially soon after diagnosis. Although improvements in stomach cancer survival were observed, survival remained relatively low for both blacks and whites. Primary prevention through the control of well-established risk factors would be expected to have the greatest impact on further reducing deaths from stomach cancer. Cancer 2017;123:4994-5013. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826592 | PMC |
| http://dx.doi.org/10.1002/cncr.30881 | DOI Listing |
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