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Red blood cell transfusions in neonatal intensive care units: a nationwide observational cohort study.
Arch Dis Child Fetal Neonatal Ed
January 2025
Neonatology, Leiden University Medical Centre, Leiden, The Netherlands.
Objective: To describe the use and nationwide variation of red blood cell (RBC) transfusions in neonatal intensive care units (NICUs) following the introduction of the revised national transfusion guideline in 2019.
Design And Patients: We randomly selected neonates born below 32 weeks' gestation admitted to any NICU in the Netherlands in 2020 to include in our retrospective observational cohort study.
Main Outcome Measures: Main outcome measures were the number of neonates receiving at least one transfusion, and the number of transfusions per transfused neonate.
Lip augmentation has become one of the most popular esthetic procedures globally, driven by societal standards that equate full lips with youth and sensuality. While young individuals often seek volume enhancement for lip beautification, older adults pursue lip rejuvenation to counter aging effects, such as volume loss, fine lines, and reduced definition. A range of techniques has been developed to meet these esthetic goals, but achieving natural and safe results remains a challenge.
View Article and Find Full Text PDFThe Political Sociology of NICE: Investigating Pharmaceutical Cost-Effectiveness Regulation in the UK.
Sociol Health Illn
January 2025
Department of Global Health and Social Medicine, King's College London, London, UK.
The National Institute for Health and Care Excellence (NICE) was established a quarter of a century ago in 1999 to regulate the cost-effectiveness of pharmaceuticals (and other health technologies) for the NHS. Drawing on medical sociology theories of corporate bias, neoliberalism, pluralism/polycentricity and regulatory capture, the purpose of this article is to examine the applicability of those theories to NICE as a key regulatory agency in the UK health system. Based on approximately 7 years of documentary research, interviews with expert informants and observations of NICE-related meetings, this paper focuses particularly on NICE's relationship with the interests of the pharmaceutical industry compared with other stakeholder interests at the meso-organisational level.
View Article and Find Full Text PDFComparing machine learning techniques for neonatal mortality prediction: insights from a modeling competition.
Pediatr Res
December 2024
Washington University in St. Louis, Department of Pediatrics, Division of Newborn Medicine, St. Louis, MO, USA.
Background: Predicting mortality risk in neonatal intensive care units (NICUs) is challenging due to complex, variable clinical and physiological data. Machine learning (ML) offers potential for more accurate risk stratification.
Objective: To compare the performance of various ML models in predicting NICU mortality using a team-based modeling competition.
Epidemiology of major heart rhythm and conduction disorders.
Arch Cardiovasc Dis
December 2024
Cardiovascular and Neurovascular Disease Surveillance Unit, Santé Publique France, 94410 Saint-Maurice, France.
Article Synopsis
- Heart rhythm and conduction disorders vary in severity and can be benign or life-threatening, with a focus on their epidemiology in France.
- A study analyzed hospitalization data from 2022 and mortality from 2021 to assess the prevalence of three main conditions: atrial fibrillation/flutter, conduction disorders, and ventricular tachycardia/cardiac arrest.
- Findings revealed over 2.7 million individuals impacted by these disorders as of January 2023, with significant hospitalization rates and a concerning 44% mortality rate for those hospitalized due to ventricular tachycardia/cardiac arrest.
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