AI Article Synopsis
- The study investigates the link between smoking and new events of peripheral vestibular disorder (PVD) in adults aged 20 and older, focusing on 393 participants treated for chronic conditions.
- There was a significant association found, with ever-smokers at a higher risk for developing PVD compared to never-smokers, particularly for those with a smoking history of 30 pack-years or more.
- The findings highlight that male smokers, especially those with a higher pack-year history, face a greater risk of new PVD events, suggesting that smoking cessation could help prevent such occurrences in this group.
Article Abstract
Common inner ear diseases include peripheral vestibular disorder (PVD) and hearing impairment. The association between smoking and peripheral vestibular disorder (PVD) is unclear. We examined associations between smoking and new PVD events. In this retrospective study, we consecutively enrolled 393 participants aged ≥20 years [mean age 65.3 years; males 133 (33.8%)] treated for hypertension, dyslipidaemia, or diabetes mellitus at a primary care clinic between November 2011 and March 2013. Participants were categorized as ever-smokers (including current and past -smokers; divided per <30 and ≥30 pack-years), and never-smokers. New PVD events were reported over a 1-year follow-up period. Hazard ratios (HR) for new onset PVD were estimated using the Cox proportional hazard regression model. Compared to never-smokers, the adjusted HR was 2.22 for ever-smokers and 2.70 for all ever-smokers with ≥30 pack-years among all 393 participants. Among male participants, compared to never-smokers, the adjusted HR was 4.41 for ever-smokers with ≥30 pack-years. A smoking history of ≥30 pack-years was strongly associated with the risk of new onset PVD in males but not, females. This study may assist patients with smoking cessation for the prevention of new PVD events among males.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715055 | PMC |
| http://dx.doi.org/10.1038/s41598-017-17294-1 | DOI Listing |
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