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Cross-Sectional Analysis of Hypoxia-Regulated , , HIF-1α, and SIRT1 in the Development of Type 2 Diabetes in Patients with Obstructive Sleep Apnea-Preliminary Study.
J Clin Med
December 2024
Department of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 90-419 Lodz, Poland.
: Obstructive sleep apnea (OSA) is recognized as an independent risk factor for diabetes mellitus type 2 (T2DM) development, which is twice as common in patients with OSA compared to non-OSA patients. : This study aimed to investigate changes in oxygen metabolism and their role in T2DM development among OSA patients through epigenetic processes via , , and enzymatic processes via SIRT1 and HIF-1α. : Based on polysomnography, apnea-hypopnea index and the presence of T2DM patients were divided into three groups: control group ( = 17), OSA group ( = 11), OSA&T2DM ( = 20) group.
View Article and Find Full Text PDFBackground: CRP is a hepatic acute-phase reactant protein, which is primarily induced by the interleukin-6 action due to an inflammatory/infectious process. Precision is closeness of agreement between indications or measured quantity values obtained by replicate measurements on the same or similar objects under specified conditions. Precision goals should be stated as the maximum allowable imprecision, SD, and/or CV expressed as a percentage (% CV) at each analyte´s concentration to be tested.
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- The study aimed to compare the effectiveness of two antihypertensive therapies, spironolactone and eplerenone, in treating patients with essential arterial hypertension and atrial fibrillation.
- It involved 99 patients, who were divided into two groups, each receiving one of the therapies for six months, with various health measurements taken to assess their condition.
- Results showed that a higher percentage of patients on eplerenone reached target diastolic blood pressure levels compared to those on spironolactone (87.8% vs. 67.5%).
Using seasonal physiological and biochemical responses to select forest components adapted to soybean and corn intercropping.
Heliyon
August 2024
Instituto Federal de Educação, Ciência e Tecnologia Goiano, Rio Verde Campus, Rodovia Sul Goiana, Km 01, Zona Rural, Rio Verde, 75.901-970, GO, Brazil.
Given the increasing utilization of forest components in integration systems worldwide, coupled with the growing demand for food in regions facing water restrictions, this study aims to evaluate how physiological and biochemical parameters contribute to the diversification of adaptive mechanisms among native species and eucalyptus genotypes intercropped with soybean or corn. The native tree species and , and the eucalyptus genotypes Urograndis I-144 and Urocam VM01, were grown in soybean and corn intercropping areas and evaluated in fall, winter, spring, and summer. The study evaluated morning water potential, chloroplast pigment concentration, gas exchange, cell damage, and antioxidant enzyme activity.
View Article and Find Full Text PDFUnique properties of titanium dioxide quantum dots assisted regulation of growth and biochemical parameters of Hibiscus sabdariffa plants.
BMC Plant Biol
February 2024
Physics Department, Faculty of Science, Zagazig University, Zagazig, Sharqia, 44519, Egypt.
Owing to the uniqueness of quantum dots (QDs) as a potential nanomaterial for agricultural application, hence in the present study, titanium dioxide quantum dots (TiO QDs) were successfully synthesized via sol-gel technique and the physico-chemical properties of the prepared TiO QDs were analyzed. Based on the results, the TiO QDs showed the presence of anatase phase of TiO. TEM examination revealed spherical QDs morphology with an average size of 7.
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