Background: Falls among hospitalised patients contribute to avoidable morbidity and prolonged hospital stay. We aimed to describe the incidence, circumstances and outcomes associated with patient falls occurring in intensive care units.
Methods: Retrospective cohort study of adult admissions to an academic, tertiary ICU in Edmonton, Canada between 1 January 2013 and 30 April 2016. Fall events were ascertained by interrogation of an electronic health record. Each fall was independently adjudicated by two intensivists to confirm that a fall did occur, and to determine if the fall was potentially avoidable. Agreement was assessed by intraclass correlation (ICC). A matched cohort (one fall to five non-fall) was created to compare course and outcomes.
Results: Of 31 events identified, 26 were adjudicated as a fall (84%), for an estimated incidence of 5.2 per 1000 ICU admissions (95% CI, 3.4-7.6). Of these, 23 were judged as avoidable (89%) (ICC, 0.69; 95% CI, 0.37-0.85). The mean age was 54.5 years (SD, 17.4 years), 20 of the falls (77%) involved men, and 10 (39%) were surgical admissions (eight [31%] for trauma). The median ICU stay before the falls was 10.6 days (interquartile range [IQR], 6.2-15.0 days), and 13 patients (50%) scored positive for delirium. At the time of the fall, three patients (12%) were invasively ventilated, and eight (31%) were classified as ward-ready. Eleven falls (42%) were witnessed and 12 (46%) occurred after hours, of which nine involved patients (75%) who had delirium. Seven falls (27%) occurred within 2 hours of a nursing shift change and 11 (42%) during a nursing break coverage. No patient sustained a major injury related to a fall but four (15%) reported minor injuries such as a laceration or abrasion. The median ICU stay after a fall was 2.2 days (IQR, 1.2-2.9 days). Compared with the matched non-fall cohort, patients who fell had a longer duration of ICU stay (median, 12.0 days [IQR, 8.3-18.6 days] v 4.7 days [IQR, 2.8-8.4 days]; P < 0.0001).
Conclusion: Falls in the ICU are infrequent and generally perceived as avoidable. Falls often occur at night, are unwitnessed and are associated with concomitant patient delirium and nursing shift changes and cross coverage.
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Shock
January 2025
Department of Industrial and Systems Engineering, University of Florida, P.O. Box 116595, Gainesville, FL, 32611, USA.
Understanding clinical trajectories of sepsis patients is crucial for prognostication, resource planning, and to inform digital twin models of critical illness. This study aims to identify common clinical trajectories based on dynamic assessment of cardiorespiratory support using a validated electronic health record data that covers retrospective cohort of 19,177 patients with sepsis admitted to ICUs of Mayo Clinic Hospitals over eight-year period. Patient trajectories were modeled from ICU admission up to 14 days using an unsupervised machine learning two-stage clustering method based on cardiorespiratory support in ICU and hospital discharge status.
View Article and Find Full Text PDFActa Radiol
January 2025
Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Background: Cesarean hysterectomy in the placenta accreta spectrum (PAS) remains challenging due to difficulty in controlling perioperative bleeding.
Purpose: To compare the effectiveness and safety of perioperative balloon occlusion with versus without pelvic artery embolization in PAS women who underwent a cesarean hysterectomy.
Material And Methods: A total of 26 pathological confirmed cases of PAS were retrospectively reviewed and categorized into two groups: perioperative balloon occlusion at either the anterior division of the internal iliac artery or uterine artery followed by gelfoam embolization (n = 12, study group) and perioperative balloon occlusion alone (n = 14, control group).
Front Med (Lausanne)
January 2025
College of Medicine, Chungbuk National University, Cheongju, Republic of Korea.
Introduction: Sepsis, a life-threatening condition with a high mortality rate, requires intensive care unit (ICU) admission. The increasing hospitalization rate for patients with sepsis has escalated medical costs due to the strain on ICU resources. Efficient management of ICU resources is critical to addressing this challenge.
View Article and Find Full Text PDFOptimal dosing of VTE prophylaxis for specific patient populations remains an area of concern as insufficient evidence exists regarding dosing for underweight patients. The purpose of this study is to compare the incidence of major bleeding events in underweight patients given different prophylactic doses of enoxaparin. This is a retrospective analysis performed at multiple hospitals within a single health care system.
View Article and Find Full Text PDFFront Oncol
January 2025
Department of Nuclear Medicine, Mount Sinai Hospital at Icahn School of Medicine, New York, NY, United States.
Peptide receptor radionuclide therapy (PRRT) is used for the management of neuroendocrine tumors (NETs) not responsive to somatostatin analogs. In this case series, we report two patients with pancreatic vasoactive intestinal peptide (VIP)-secreting NETs (VIPomas) not responsive to any other therapies who achieved symptomatic control and a significant decrease in serum VIP levels with PRRT during their hospital stay. Two patients with VIPomas were admitted to the hospital with multiple prior hospital admissions after going through multiple lines of therapy.
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