An ambiphilic phosphine/H-bond donor ligand and its application to the gold mediated cyclization of propargylamides.

Chem Commun (Camb)

Department of Chemistry, Texas A&M University, College Station, Texas 77843, USA.

Published: December 2017

We describe the synthesis of an ambiphilic phosphine/H-bond donor ligand featuring a trifluoroacetamide functionality, its coordination to gold(i) chloride, and its application as a self-activating catalyst for the cyclization of propargylamides.

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Source
http://dx.doi.org/10.1039/c7cc06065cDOI Listing

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