Lignocellulosic ethanol has been considered as an alternative transportation fuel. Utilization of hemicellulosic fraction in lignocelluloses is crucial in economical production of lignocellulosic ethanol. However, this fraction has not efficiently been utilized by traditional yeast Saccharomyces cerevisiae. Genetically modified S. cerevisiae, which can utilize xylose, has several limitations including low ethanol yield, redox imbalance, and undesired metabolite formation similar to native xylose utilizing yeasts. Besides, xylose uptake is a major issue, where sugar transport system plays an important role. These genetically modified and wild-type yeast strains have further been engineered for improved xylose uptake. Various techniques have been employed to facilitate the xylose transportation in these strains. The present review is focused on the sugar transport machineries, mechanisms of xylose transport, limitations and how to deal with xylose transport for xylose assimilation in yeast cells. The recent advances in different techniques to facilitate the xylose transportation have also been discussed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jbiosc.2017.10.006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Advances in fungal sugar transporters: unlocking the potential of second-generation bioethanol production.
Appl Microbiol Biotechnol
January 2025
Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, 14049-900, Brazil.
Second-generation (2G) bioethanol production, derived from lignocellulosic biomass, has emerged as a sustainable alternative to fossil fuels by addressing growing energy demands and environmental concerns. Fungal sugar transporters (STs) play a critical role in this process, enabling the uptake of monosaccharides such as glucose and xylose, which are released during the enzymatic hydrolysis of biomass. This mini-review explores recent advances in the structural and functional characterization of STs in filamentous fungi and yeasts, highlighting their roles in processes such as cellulase induction, carbon catabolite repression, and sugar signaling pathways.
View Article and Find Full Text PDFAlcoholysis of High-Solid xylose residue for methyl levulinate preparation and its kinetics.
Bioresour Technol
January 2025
School of Chemical Engineering, Zhengzhou University, Zhengzhou 450001, China; Henan Center for Outstanding Overseas Scientists, Zhengzhou 450001, China. Electronic address:
Achieving the efficient biomass alcoholysis to methyl levulinate (ML) under high solid content conditions and establishing its kinetic model are crucial, but remain challenging. Here, the alcoholysis of microcrystalline cellulose (MC) and xylose residue (XR) to ML under high solid content conditions using CuSO as a catalyst was reported. High yield (34.
View Article and Find Full Text PDFExpression of a periplasmic β-glucosidase from Yarrowia lipolytica allows efficient cellobiose-xylose co-fermentation by industrial xylose-fermenting Saccharomyces cerevisiae strains.
Braz J Microbiol
December 2024
Laboratory of Yeast Biochemistry (LabBioLev), Federal University of Fronteira Sul, Campus Chapecó, Chapecó, SC, Brazil.
This study aimed to compare the effects of cellobiose hydrolysis, whether occurring inside or outside the cell, on the ability of Saccharomyces cerevisiae strains to ferment this sugar and then apply the most effective strategy to industrial S. cerevisiae strains. Firstly, two recombinant laboratory S.
View Article and Find Full Text PDFRegulatory Role of Vacuolar Calcium Transport Proteins in Growth, Calcium Signaling, and Cellulase Production in .
J Fungi (Basel)
December 2024
Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Recent research has revealed the calcium signaling significance in the production of cellulases in . While vacuoles serve as the primary calcium storage within cells, the function of vacuolar calcium transporter proteins in this process remains unclear. In this study, we conducted a functional characterization of four vacuolar calcium transport proteins in .
View Article and Find Full Text PDFGenomic characteristics and genetic manipulation of the marine yeast Scheffersomyces spartinae.
Appl Microbiol Biotechnol
December 2024
National Key Laboratory of Biobased Transportation Fuel Technology, Ocean College, Zhejiang University, Hangzhou, 310027, China.
The halotolerant yeast Scheffersomyces spartinae, commonly found in marine environments, holds significant potential for various industrial applications. Despite this, its genetic characteristics have been relatively underexplored. In this study, we isolated a strain of S.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!