Daptomycin β-Lactam combination therapy offers "protection" against daptomycin non-susceptibility (DNS) development in Enterococcus faecium. We report failure of this strategy and the importance of source control. Mutations were detected in the LiaF and cls genes in DNS isolates. A single DNS isolate contained an unrecognized mutation, which requires confirmation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.diagmicrobio.2017.10.017 | DOI Listing |
Publication Analysis
Top Keywords
daptomycin β-lactam
8
β-lactam combination
8
combination therapy
8
enterococcus faecium
8
failure daptomycin
4
therapy prevent
4
prevent resistance
4
resistance emergence
4
emergence enterococcus
4
faecium daptomycin
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!