Long-noncoding RNAs (lncRNAs) are emerging as important regulators of cellular processes, but few have been functionally characterized in host-pathogen interactions. A recent report in Science demonstrates a mechanistic role for a novel lncRNA in directly binding an essential metabolic enzyme, glutamic-oxaloacetic transaminase (GOT2); this interaction benefits viral replication via alteration of host metabolism.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799814 | PMC |
| http://dx.doi.org/10.1038/cr.2017.153 | DOI Listing |
Publication Analysis
Top Keywords
gotcha lncrna-acod1
4
lncrna-acod1 targets
4
targets metabolism
4
metabolism viral
4
viral infection
4
infection long-noncoding
4
long-noncoding rnas
4
rnas lncrnas
4
lncrnas emerging
4
emerging regulators
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!