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Effectiveness of interventions to prevent or treat prolonged grief symptoms among families of patients who die in Intensive Care Units: a systematic review protocol.
JBI Evid Synth
January 2025
CINTESIS@RISE, Nursing School of Porto (ESEP), Porto, Portugal.
Objective: The objective of this review is to evaluate the effectiveness of interventions to prevent or treat prolonged grief symptoms among families of patients who die in intensive care units (ICU).
Introduction: Up to 52% of families of patients who die in ICU may be at risk of experiencing prolonged grief symptoms.
Inclusion Criteria: Studies of adult family members (≥18 years) of adult ICU patients (≥18 years) who underwent a treatment withdrawal or withholding decision, and who were exposed to tailored interventions to prevent or treat prolonged grief symptoms before, during, and/or after the patient's death will be considered for inclusion.
Combination of clinical factors predicts successful glucocorticoid withdrawal in systemic lupus erythematosus (SLE): results from a multicentre, retrospective cohort study.
RMD Open
January 2025
Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S.Anna, Ferrara, Italy.
Objective: Glucocorticoid (GC) tapering and withdrawal to reduce damage represents a key aspect of the European Alliance of Associations for Rheumatology (EULAR) SLE recommendations. However, optimal strategies for relapse-free GC cessation remain ill-defined. We characterised clinical predictors and their combined effect on flares in patients with SLE who discontinued GC.
View Article and Find Full Text PDFConscience at the End of Life.
Nurs Rep
December 2024
Department of Philosophy, Idaho State University, Pocatello, ID 83209, USA.
Background/objectives: Caring for patients at the end of life can involve issues that are ethically and legally fraught: withholding or withdrawing artificial nutrition and hydration, pain control that could hasten death, aggressive treatment that is continued when it seems only to be prolonging suffering, patients who request medical assistance in dying, and so forth. Clinicians may find that their deeply held ethical principles conflict with law, institutional policy, or patients' choices. In these situations, they may consider either refusing to participate in procedures that they find morally abhorrent (conscientious refusal) or providing care that they believe to be ethically obligatory despite being contrary to law or policy (conscientious commitment).
View Article and Find Full Text PDFIn-hospital and delayed mortality in patients with upper gastrointestinal bleeding on antithrombotic treatment: effects of withdrawal and resuming.
Postgrad Med
January 2025
Department of Gastroenterology, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Background: Antithrombotic drugs pose a dual challenge to acute upper gastrointestinal bleeding, with associated risks of bleeding complications and thromboembolic events upon withdrawal. We aimed to determine the impact of antithrombotic medications on in-hospital and delayed outcomes and whether suspension and resumption influenced delayed mortality.
Methods: This study was a prospective registry analysis of patients between 2013-2021.
Predictors of End-of-Life Care in Nonelderly Adults With Severe Traumatic Brain Injury.
J Surg Res
December 2024
Division of Trauma & Acute Care Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address:
Introduction: Older age is a well-established risk factor for withdrawal of life-sustaining therapy (WDLST) and discharge to hospice (DH) in traumatic brain injury (TBI). However, a paucity of data exists in identifying factors associated with end-of-life (EoL) care in younger patients with TBI. We sought to identify hospital and patient factors associated with EoL care and timing of EoL care in younger adults with severe TBI.
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