Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1530/ERC-17-0453 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Early Improvements With Atogepant for the Preventive Treatment of Migraine: Results From 3 Randomized Phase 3 Trials.
Neurology
January 2025
AbbVie, North Chicago, IL; and.
Background And Objectives: Three phase 3 trials demonstrated the efficacy and safety of atogepant in episodic migraine (EM) and chronic migraine (CM) across 12-week treatment periods. This analysis evaluates improvements in efficacy and functional outcomes in the first 4 weeks of treatment with the oral calcitonin gene-related peptide receptor antagonist, atogepant, for the preventive treatment of migraine.
Methods: ADVANCE, ELEVATE, and PROGRESS were phase 3, multicenter, randomized, double-blind, placebo-controlled 12-week trials.
An international and multidisciplinary EORTC survey on resectability of stage III non-small cell lung cancer.
Lung Cancer
December 2024
Department of Pulmonary Medicine, GROW - School for Oncology and Reproduction, Maastricht University Medical Center+, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands. Electronic address:
Introduction: The EORTC-Lung Cancer Group initiated a Delphi consensus process to establish a consensual definition of resectable stage III non-small cell lung cancer (NSCLC) for the use in clinical trials, including a systematic review, survey, and review of clinical cases. Here, the survey results are presented, aimed to identify areas of controversy.
Methods: A survey was distributed among the members of six international organizations related to lung cancer.
Automated Pathologic TN Classification Prediction and Rationale Generation From Lung Cancer Surgical Pathology Reports Using a Large Language Model Fine-Tuned With Chain-of-Thought: Algorithm Development and Validation Study.
JMIR Med Inform
December 2024
Office of eHealth Research and Business, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Background: Traditional rule-based natural language processing approaches in electronic health record systems are effective but are often time-consuming and prone to errors when handling unstructured data. This is primarily due to the substantial manual effort required to parse and extract information from diverse types of documentation. Recent advancements in large language model (LLM) technology have made it possible to automatically interpret medical context and support pathologic staging.
View Article and Find Full Text PDFPrognostic performance of the N category in the 9th edition of lung cancer staging.
Eur Radiol
December 2024
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
Objectives: To compare the prognostic performance of the N category of lung cancer in the 9th edition with previous editions (7th edition and 8th edition's proposal).
Methods: Patients who underwent lobectomy or pneumonectomy for lung cancer from January 2015 to December 2021 were retrospectively analyzed. Clinical and pathologic N categories were reclassified according to the 9th edition (N0, N1, N2a, and N2b), the 8th edition's proposal (N0, N1a, N1b, N2a1, N2a2, and N2b), and the 7th edition (N0, N1, and N2).
Tribuli Fructus alleviates 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease by suppressing neuroinflammation via JNK signaling.
Metab Brain Dis
December 2024
Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, 02447, Seoul, Republic of Korea.
Parkinson's disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons. In particular, neuroinflammation associated with phosphorylation of c-Jun N-terminal kinase (JNK) is likely to cause the death of dopaminergic neurons. Therefore, protecting dopaminergic neurons through anti-neuroinflammation is a promising therapeutic strategy for PD.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!