Dynamics of the human brain network revealed by time-frequency effective connectivity in fNIRS.

Biomed Opt Express

Movement Disorders and Neurostimulation, Biomedical Statistics and Multimodal Signal Processing Unit, Department of Neurology, Focus Program Translational Neuroscience (FTN), Department of Neurology, Johannes Gutenberg University, Mainz, Germany.

Published: November 2017

Functional near infrared spectroscopy (fNIRS) is a promising neuroimaging method for investigating networks of cortical regions over time. We propose a directed effective connectivity method (TPDC) allowing the capture of both time and frequency evolution of the brain's networks using fNIRS data acquired from healthy subjects performing a continuous finger-tapping task. Using this method we show the directed connectivity patterns among cortical motor regions involved in the task and their significant variations in the strength of information flow exchanges. Intra and inter-hemispheric connections during the motor task with their temporal evolution are also provided. Characterisation of the fluctuations in brain connectivity opens up a new way to assess the organisation of the brain to adapt to changing task constraints, or under pathological conditions.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695973PMC
http://dx.doi.org/10.1364/BOE.8.005326DOI Listing

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