AI Article Synopsis
- The rodent olfactory systems (main and accessory) have distinct functions for detecting odors and pheromones, but recent research shows they may work together more than previously thought.
- Four newly discovered receptor families in the nasal cavity suggest alternative pathways for processing sensory information, influencing specific behaviors.
- These pathways converge in a less understood region called the olfactory limbus, which may play a role in processing both typical and atypical sensory information.
Article Abstract
The rodent main and accessory olfactory systems (AOS) are considered functionally and anatomically segregated information-processing pathways. Each system is devoted to the detection of volatile odorants and pheromones, respectively. However, a growing number of evidences supports a cooperative interaction between them. For instance, at least four non-canonical receptor families (i.e., different from olfactory and vomeronasal receptor families) have been recently discovered. These atypical receptor families are expressed in the sensory organs of the nasal cavity and furnish parallel processing-pathways that detect specific stimuli and mediate specific behaviors as well. Aside from the receptor and functional diversity of these sensory modalities, they converge into a poorly understood bulbar area at the intersection of the main- main olfactory bulb (MOB) and accessory olfactory bulb (AOB) that has been termed olfactory limbus (OL). Given the intimate association the OL with specialized glomeruli (i.e., necklace and modified glomeruli) receiving uncanonical sensory afferences and its interactions with the MOB and AOB, the possibility that OL is a site of non-olfactory and atypical vomeronasal sensory decoding is discussed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695156 | PMC |
| http://dx.doi.org/10.3389/fnana.2017.00108 | DOI Listing |
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