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Unlabelled: Transparent and accurate reporting in early phase dose-finding (EPDF) clinical trials is crucial for informing subsequent larger trials. The SPIRIT statement, designed for trial protocol content, does not adequately cover the distinctive features of EPDF trials. Recent findings indicate that the protocol contents in past EPDF trials frequently lacked completeness and clarity.
View Article and Find Full Text PDFCan social pain be medicated away? A pilot study on everyday discrimination and its exacerbation of opioid misuse risk in people of color with chronic pain.
Health Psychol Behav Med
January 2025
Department of Psychology, University of Florida, Gainesville, FL, USA.
Despite mounting evidence of a robust relation between discrimination and poor pain outcomes in people of color (POC) with chronic pain, little is known about everyday discrimination's role in increasing the risk of opioid misuse and its potential interactive effects. This study aimed to evaluate the potential moderating effect of everyday discrimination on the relationship between chronic pain severity and the risk of opioid misuse among POC with chronic pain. Everyday discrimination was assessed using the 9-item Everyday Discrimination Scale (EDS), while the risk of opioid misuse was measured with the 14-item Screener and Opioid Assessment for Patients with Pain (SOAPP).
View Article and Find Full Text PDFQuality of life among Indonesian family caregivers caring for dependent older persons with type 2 diabetes mellitus in the community: A cross-sectional, correlational study.
Belitung Nurs J
January 2025
School of Nursing and Midwifery, Faculty of Health, University of Plymouth, Plymouth, United Kingdom.
Background: The global prevalence of older adults with diabetes has increased, and family caregivers in Indonesia play a critical role in managing diabetes and providing personal care. However, caregiving can be complex and challenging, often negatively affecting caregivers' quality of life (QoL).
Objective: This study aimed to develop and test a hypothesized causal model of QoL among Indonesian family caregivers who care for dependent older persons with type 2 diabetes mellitus (T2DM) in 2024.
Mothers' experiences as legal guardian of children's phlebitis during hospitalization in Indonesia: A phenomenological study.
Belitung Nurs J
January 2025
STIKes Mitra Keluarga, West Java, Indonesia.
Background: Peripheral intravenous catheter (PIVC) insertion is a common procedure performed by nurses for hospitalized children, but phlebitis-an inflammation of the vein-is a frequent complication. The response of the mother, as the child's primary caregiver, plays a key role in the healing process when phlebitis occurs.
Objective: This study aimed to explore mothers' experiences and perceptions regarding the occurrence and management of phlebitis in their children during hospitalization.
The correlations between demographic factors, self-efficacy, and quality of life among Indonesian patients with ischemic stroke: A cross-sectional study.
Belitung Nurs J
January 2025
Department of Nursing, Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
Background: Ischemic stroke is the primary cause of neurological disability and can lead to psychological issues that affect self-efficacy. Changes in self-efficacy, in turn, influence the overall quality of life. Although many studies have examined factors that affect self-efficacy, quality of life, or both, few have specifically explored the role of demographic factors in shaping the quality of life in patients with ischemic stroke.
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