AI Article Synopsis
- The exact causes of female pattern hair loss remain unclear, but it may involve genetic, hormonal, and environmental factors.
- Environmental pollutants activating the aryl hydrocarbon receptor in skin cells can disrupt normal cell processes, possibly contributing to hair loss.
- The study found that nuclear aryl hydrocarbon receptors are overexpressed in the miniaturized hair follicles of women experiencing this type of hair loss.
Article Abstract
The etiopathogenesis of female pattern hair loss is still poorly understood. In addition to genetic and hormonal elements, environmental factors could be involved. The aryl hydrocarbon receptor is expressed in keratinocytes and can be activated by environmental pollutants leading to alterations in the cell cycle, inflammation, and apoptosis. Here we demonstrate the overexpression of nuclear aryl hydrocarbon receptors in miniaturized hair follicles in female pattern hair loss.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514597 | PMC |
| http://dx.doi.org/10.1590/abd1806-4841.20175150 | DOI Listing |
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