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Oral probiotic administration attenuates postexercise inflammation in horses.
Transl Anim Sci
August 2024
Land O Lakes, Purina Animal Nutrition, Gray Summit, MO 63039, USA.
Probiotics are commonly incorporated into equine diets to impart health and performance benefits; however, peer-reviewed evidence supporting their efficacy in horses is limited. Interestingly, bacteria from the genus are gaining interest for their unique ability to impact metabolic, immune, and inflammatory pathways. The objective of this trial was to evaluate a selection of for their role in altering the inflammatory response in horses to exercise.
View Article and Find Full Text PDFEnabling equitable and affordable access to novel therapeutics for pandemic preparedness and response via creative intellectual property agreements.
Wellcome Open Res
July 2024
Drugs for Neglected Diseases initiative (DNDi), Geneva, 1202, Switzerland.
The COVID-19 pandemic demonstrated that the current purely market-driven approaches to drug discovery and development alone are insufficient to drive equitable access to new therapies either in preparation for, or in response to, pandemics. A new global framework driven by equity is under negotiation at the World Health Organization to support pandemic preparedness and response. Some believe that the global intellectual property (IP) system itself is part of the problem and propose a purely Open Science approach.
View Article and Find Full Text PDFPatient safety advisory boards and risk evaluation.
Heart Rhythm
August 2023
University of Maryland, School of Medicine, Baltimore, Maryland.
Revisioning aging: Indigenous, crip and queer renderings.
J Aging Stud
December 2022
Trent Centre for Aging and Society, Trent University, 1600 West Bank Drive, Peterborough/Nogojiwanong, ON K9L 0G2, Canada.
In this article, we re-vision Anishinaabe, crip and queer futures of aging against and beyond dominant successful aging narratives by drawing on our archive of digital/multimedia videos (short documentaries) produced in conjunction with older/e/Elder persons and the Re•Vision: Centre for Art and Social Justice. These documentaries are directed and come from the lives of those older and e/Elder persons whose aging embodiments intra-sect with their Indigenous, disabled and queer selves. Disrupting hegemonic successful aging narratives, and specifically heteronormative and ableist trajectories of aging, these alternative renderings of aging futures offer rich, affective relationalities and cyclical timescapes of older experience that draw on the past even as they reach into divergent futurities.
View Article and Find Full Text PDFMetabolomic Profiles in Starved Light Breed Horses during the Refeeding Process.
Animals (Basel)
September 2022
Department of Animal Science, University of Tennessee, 2506 River Drive, Knoxville, TN 37996, USA.
The large population of emaciated horses continues to be an issue troubling the equine industry. However, little is known regarding the collection of equine metabolites (metabolome) during a malnourished state and the changes that occur throughout nutritional rehabilitation. In this study, ten emaciated horses underwent a refeeding process, during which blood samples were collected for a blood chemistry panel and metabolomics analysis via ultrahigh performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS).
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