The aim of this study was to evaluate concentration-dependent antioxidant and anticancer activities of CA and RA in ethanol extracts of three different Oregano species ( L., L., and ssp. ). The study revealed the highest RA antioxidant activity in ssp. (9550 ± 95 mmol/g) and the lowest in L. (2605 ± 52 mmol/g) ( < 0.05). The highest CA amount was present in L., which was 1.8 and 4.7 times higher ( < 0.05) than in ssp. and . L., respectively. The anticancer activity was evaluated on human glioblastoma (U87) and triple-negative breast cancer (MDA-MB231) cell lines . RA anticancer activity was negligible. CA and the extracts were about 1.5-2 times more active against MDA-MB231 cell line ( < 0.05) compared to U87 cell line. The anticancer activities of three tested extracts were similar against U87 cell line ( > 0.05) but they had different activities against MDA-MB231 cell line.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664182 | PMC |
| http://dx.doi.org/10.1155/2017/1681392 | DOI Listing |
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