AI Article Synopsis
- - The study examined the atrial arrhythmogenic features in patients with Brugada syndrome, comparing them to a control group and patients with paroxysmal atrial fibrillation (PAF) using a technique called signal-averaged electrogram (SAECG).
- - Results showed that the filtered P wave duration (fPd) was significantly longer in PAF patients compared to both the control and Brugada groups, while the Brugada group had a fPd that was longer than the control but shorter than the PAF group.
- - The findings suggest that patients with Brugada syndrome display abnormal P waves on the SAECG, indicating their P wave characteristics are intermediate between healthy individuals and those with PAF. *
Article Abstract
Background: Ventricular fibrillation and atrial fibrillation are well-known arrhythmias in patients with Brugada syndrome. This study evaluated the characteristics of the atrial arrhythmogenic substrate using the signal-averaged electrogram (SAECG) in patients with Brugada syndrome.
Methods: SAECGs were performed during normal sinus rhythm in 23 normal volunteers (control group), 21 patients with paroxysmal atrial fibrillation (PAF; PAF group), and 21 with Brugada syndrome (Brugada group).
Results: The filtered P wave duration (fPd) in the control, Brugada, and PAF groups was 113.9±12.9ms, 125.3±15.0ms, and 137.1±16.3ms, respectively. The fPd in the PAF group was significantly longer compared to that in the control and Brugada groups (p<0.05). The fPd in the Brugada group was significantly longer than that in the control group (p<0.05) and significantly shorter than that in the PAF group (p<0.05).
Conclusion: Patients with Brugada syndrome had abnormal P waves on the SAECG. The abnormal P waves on the SAECG in Brugada syndrome patients may have intermediate characteristics between control and PAF patients.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717291 | PMC |
| http://dx.doi.org/10.1016/j.ihj.2017.05.008 | DOI Listing |
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