Objective: To retrospectively evaluate the feasibility of CT fluoroscopy-guided percutaneous marking using a 25-gauge needle and indigo carmine before video-assisted thoracoscopic surgery (VATS) for small lung lesions.
Methods: 21 patients, 14 males and 7 females, with a median age of 69 years (range, 40-79), underwent CT fluoroscopy-guided percutaneous VATS marking using a 25-gauge, 70-mm needle and 1.5-ml indigo carmine. The mean diameter of the lung lesions was 14 mm (range, 6-27). We evaluated the technical success rate, surgical success rate and complications related to this procedure by reviewing medical records and images. Technical success was defined as completion of this procedure. Surgical success was defined as resection of the target lesion with negative margins on pathological examination after VATS. Complications that required advanced levels of care were classified as major complications, and the remaining complications were considered minor.
Results: The technical success rate was 100%. In all cases, VATS was successfully performed as planned, and the target lesion was resected with negative margins on pathological examination after VATS. Thus, the surgical success rate was 100%. Mild pneumothorax was found in two cases, but further treatment was not required. The minor complication rate was 9.5% (2/21), and major complication rate was 0%. Only two patients (9.5%) complained of slight pain upon puncture, but local anaesthesia was not required.
Conclusion: Percutaneous CT fluoroscopy-guided VATS marking using a 25-gauge needle without local anaesthesia appears feasible and safe. Advances in knowledge: This technique expands a possibility of the CT-guided marking.
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http://dx.doi.org/10.1259/bjr.20170692 | DOI Listing |
J Neurol Sci
January 2025
Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA. Electronic address:
Background: Craniocervical junction dural arteriovenous fistulas (CCJ-DAVFs) are rare and complex vascular malformations that are challenging to diagnose and treat. This study aims to compare surgical and endovascular treatments for CCJ-DAVFs through a systematic review and meta-analysis.
Methods: A systematic review and meta-analysis was conducted according to the PRISMA guidelines.
Ann Surg Oncol
January 2025
Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Background: Three dimensional (3D) cell cultures can be effectively used for drug discovery and development but there are still challenges in their general application to high-throughput screening. In this study, we developed a novel high-throughput chemotherapeutic 3D drug screening system for gastric cancer, named 'Cure-GA', to discover clinically applicable anticancer drugs and predict therapeutic responses.
Methods: Primary cancer cells were isolated from 143 fresh surgical specimens by enzymatic treatment.
Pediatr Crit Care Med
February 2025
Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children NHS Foundation Trust and NIHR Biomedical Research Centre, London, United Kingdom.
Objective: The Sedation and Weaning in Children (SANDWICH) trial of a sedation weaning and ventilator liberation bundle had a primary outcome of time to successful extubation, and showed significant but small difference. We explored the impact of the intervention on infants with bronchiolitis.
Design: Post hoc subgroup analysis of a cluster-randomized trial, 2018 to 2019 (ISRCTN16998143).
J Anat
January 2025
Museo Argentino de Ciencias Naturales "Bernardino Rivadavia", CONICET, Buenos Aires, Argentina.
Notosuchia were a successful lineage of Crocodyliformes that achieved a remarkable diversity during the Cretaceous of Gondwana, particularly in South America. Although paleohistology has expanded our knowledge of the paleobiology of notosuchians, several clades of this lineage remain poorly understood in this aspect. Here we help to address this gap by conducting the first histological analysis of appendicular bones of a peirosaurid.
View Article and Find Full Text PDFJ Sep Sci
January 2025
Guangzhou Institute of Chemistry, Chinese Academy of Sciences, Guangzhou, China.
Per- and polyfluoroalkyl substances (PFAS) are a widely used class of synthetic chemicals that pose a significant global environmental and health threat due to their persistent and bioaccumulation toxicity caused by strong C-F bonds in their structures. PFAS usually exist in trace concentrations in environmental water bodies, which poses great challenges for environmental analysis. In this study, environmentally friendly cellulose was modified with polyaniline through in situ oxidative polymerization, and used as the filter paper for solid-phase extracting 23 PFAS in water.
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