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Fully Covered Stent-TIPS for Advanced HCC Patients with Portal Vein Tumor Thrombus-Related Severe Symptomatic Portal Hypertension.
J Hepatocell Carcinoma
January 2025
Department of Interventional and Vascular Surgery, Peking University First Hospital, Beijing, People's Republic of China.
Purpose: Portal vein tumor thrombus (PVTT)-related severe symptomatic portal hypertension (SPH) leads to a poor prognosis in patients with advanced hepatocellular carcinoma (HCC). Traditional transjugular intrahepatic portosystemic shunt (TIPS) using covered plus bare stent can effectively relieve SPH, however, the bare segment is susceptible to obstruction due to PVTT invasion. This study aimed to evaluate the safety and efficacy of fully covered stent-TIPS (FCS-TIPS) for treatment of PVTT-related SPH in advanced HCC patients.
View Article and Find Full Text PDFA new tube chamber system for evaluation of anterior chamber pressure during phacoemulsification tested in porcine eyes.
Int J Ophthalmol
January 2025
Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Ube City, Yamaguchi 755-8585, Japan.
Aim: To measure the optimal anterior chamber pressure (ACP) for safe phacoemulsification using a new tube chamber system with internal pressure measurement function in the porcine eye.
Methods: The 20-gauge and 21-gauge straight tips with yellow and orange sleeves, respectively, were covered by a test chamber combined with a pressure sensor for measuring ACP. This was measured for 20s from 10s after starting aspiration in the linear mode using vacuum levels of 200 and 150 mm Hg with a 20-gauge tip, and 300 and 250 mm Hg with a 21-gauge tip.
Video-based propagation of tacit knowledge during coil embolization of intracranial aneurysms.
World Neurosurg
January 2025
Department of Neurosurgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Background: Neuroendovascular treatment of cerebral aneurysms is considered a basic procedure for neurosurgeons and interventional neuroradiologists; however, its critical technical nuances, termed "tacit knowledge," are challenging to impart. This study aimed to evaluate the efficacy of our novel video recording and editing method in enhancing trainees' experience.
Methods: A wearable camera (wearable recording) and multiple media sources in a hybrid operating room (hybrid recording) were used to capture procedural details such as audio and conversation, thus enabling a re-experience.
Effect of In Situ Acid Erosion on Structural and Optical Properties of Nanoparticulated Bisacrylic Resin With Different Surface Treatments.
J Esthet Restor Dent
January 2025
Department of Dental Materials and Prosthodontics, Sao Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Objective: To evaluate the influence of in situ acid erosion on the structural and optical properties of nanoparticulate bisacrylic resin with different surface treatments, evaluating surface roughness (Ra), knoop microhardness (KHN), color change (ΔE, ΔL, ΔC, ΔH), contrast (CR) and translucency (TP).
Methods: Eighty specimens were made (n = 10 per group) and the following surface treatments were applied: U-unpolished; A-polishing with Astropol rubber tips (Ivoclar); S-Biscover LV surface sealant (Bisco) and S-Palaseal surface sealant (kulzer). For the in situ experiment, 10 volunteers wore an intraoral appliance containing eight specimens (two specimens per experimental group), with only one specimen from each experimental group being subjected to the acid process.
Data-Driven Equation-Free Dynamics Applied to Many-Protein Complexes: The Microtubule Tip Relaxation.
Biophys J
January 2025
Department of Chemistry, Chicago Center for Theoretical Chemistry, The James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, United States. Electronic address:
Microtubules (MTs) constitute the largest components of the eukaryotic cytoskeleton and play crucial roles in various cellular processes, including mitosis and intracellular transport. The property allowing MTs to cater to such diverse roles is attributed to dynamic instability, which is coupled to the hydrolysis of GTP (guanosine-5'-triphosphate) to GDP (guanosine-5'-diphosphate) within the β-tubulin monomers. Understanding the equilibrium dynamics and the structural features of both GDP- and GTP-complexed MT tips, especially at an all-atom level, remains challenging for both experimental and computational methods because of their dynamic nature and the prohibitive computational demands of simulating large, many-protein systems.
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