AI Article Synopsis
- The study sequenced the whole genomes of three strains of porcine bocaparvovirus (PBoV) using polymerase chain reaction, identifying them as part of group 3 (G3).
- Phylogenetic analysis indicated that these strains are more closely related to bocaparvoviruses from other animals rather than to other porcine strains.
- The researchers also found conserved sequences associated with phospholipase A2 activity and identified a natural recombination breakpoint in the NS1 region of PBoV G3, aiding in the understanding of PBoV epidemiology.
Article Abstract
In this study, we obtained the whole genomes of three porcine bocaparvovirus (PBoV) strains (GD6, GD10, and GD23) by polymerase chain reaction. Sequence analysis showed that all three field strains belonged to PBoV group 3 (G3). The phylogenetic trees based on NS1, NP1, and VP1 differed to the extent that these PBoVs were potentially more closely related to bocaparvoviruses known to infect other animals than to other PBoVs. GD6, GD10, and GD23 all included the conserved sequences YLGPF and HDXXY, with known phospholipase A2 activity. Using recombination-detection software we identified a natural recombinant breakpoint in the NS1 region of PBoV G3. The results of this study will further the epidemiological characterization of PBoVs.
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| http://dx.doi.org/10.1007/s00705-017-3606-8 | DOI Listing |
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