Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.nrl.2017.09.006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Autoimmune brainstem encephalitis: Clinical associations, outcomes, and proposed diagnostic criteria.
Ann Clin Transl Neurol
January 2025
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Objective: We describe neurologic phenotype, clinical associations, and outcomes in autoimmune brainstem encephalitis.
Methods: Medical records of neural-IgG positive autoimmune brainstem encephalitis patients diagnosed at Mayo Clinic (January 1, 2006-December 31, 2022) were reviewed.
Results: Ninety-eight patients (57 male) were included.
Unveiling the Enigma: A Peculiar Encounter of Concurrent Anti--methyl-D-aspartate Receptor and Anti-Hu Antibody Positive Paraneoplastic Syndrome in Small Cell Lung Cancer.
J Assoc Physicians India
December 2024
Junior Resident, Department of Medicine, AIIMS, Delhi, India.
Paraneoplastic neurological syndromes (PNS) are mostly immune-mediated, tumor-associated disorders. Earlier the 2004 PNS criteria were used which are now partially outdated due to advances in PNS research and also identification of new phenotypes and antibodies that have transformed the diagnostic approach to PNS; hence, a new criterion was proposed in 2016. They can have multifarious presentations, ranging from behavioral abnormalities to altered sensorium and coma.
View Article and Find Full Text PDFCentral sleep apnea as an initial presentation of small cell lung carcinoma with anti-Hu antibody-related paraneoplastic neurologic syndrome.
Respirol Case Rep
December 2024
Division of Critical Care Medicine, Department of Internal Medicine National Cheng Kung University Hospital Tainan Taiwan.
Anti-Hu antibody-related paraneoplastic neurologic syndrome (PNS), a rare disease primarily associated with small cell lung carcinoma, is characterized by diverse neurologic manifestations. Central sleep apnea, although rare, is specific to anti-Hu antibody-related PNS. Herein, we present a case of out-of-hospital cardiac arrest attributed to hypercapnic central sleep apnea and detail the subsequent workup that revealed anti-Hu brainstem encephalitis.
View Article and Find Full Text PDFPhenotypic and oncological insights in ANNA1 autoimmunity: Age stratification and biomarker analysis.
Ann Clin Transl Neurol
November 2024
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Objective: To describe the phenotypes, oncological associations, biomarker profiles, and outcomes across different age groups in patients with ANNA1 (anti-Hu) autoimmunity.
Methods: A retrospective review of patients with ANNA1-IgG in serum/CSF between January 1, 2001, and December 31,2019 was performed. Patients were classified into three groups based on the age of symptom onset.
Case report: Immune checkpoint inhibitor-induced paraneoplastic neurological syndrome in two patients: a case series.
Front Oncol
October 2024
Department of Respiratory and Critical Care Medicine, The General Hospital of Western Theater Command, Chengdu, China.
Immune checkpoint inhibitors (ICIs) combined with chemotherapy have improved overall survival in patients with small-cell lung cancer, but have also led to an increase in adverse effects. The incidence of ICI-induced paraneoplastic neurological syndrome (PNS) is relatively low when the primary lung lesion is well controlled. However, it is associated with high mortality and disability rates.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!