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http://dx.doi.org/10.11622/smedj.2017103 | DOI Listing |
Front Pediatr
December 2022
Pediatric Intermediate Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Ceftriaxone, a third-generation cephalosporin, is commonly used in pediatric patients and is generally well tolerated. Its more frequent adverse effects are biliary pseudolithiasis, urolithiasis, and hemolytic anemia. On the other hand, ceftriaxone-induced acute cholestatic hepatitis is a very rare condition, especially in children.
View Article and Find Full Text PDFSurg Case Rep
May 2022
Department of Surgery, Doshinkai Tohyama Hospital, Minami-Shinmachi 17-22, Tsu, Mie, 514-0043, Japan.
Background: Ceftriaxone, a third-generation cephalosporin antibiotic with a long plasma half-life, is widely used to treat various infections. The use of ceftriaxone can sometimes induce biliary sludge or stone formation. Although most cases of ceftriaxone-induced pseudolithiasis are asymptomatic or mild and resolve with discontinuation of the drug, we experienced an elderly case of severe acute necrotizing calculous cholecystitis after administration of ceftriaxone.
View Article and Find Full Text PDFJ Med Ultrasound
May 2021
Department of Radiology, Hospital de Braga, Braga, Portugal.
Ceftriaxone has been increasingly used in pediatric population, due to its bacteriological and pharmacokinetic features. Association between ceftriaxone and biliary sludge/pseudolithiasis formation has been documented in the literature. More rarely, biliary symptoms and cholecystitis during ceftriaxone therapy have been reported.
View Article and Find Full Text PDFCase Rep Med
November 2017
Department of Internal Medicine, Munakata Medical Association Hospital, Fukuoka, Japan.
Ceftriaxone (CTRX) is known to cause reversible biliary stones/sludge, which is called biliary pseudolithiasis. We report two rare cases of biliary obstruction by pseudolithiasis shortly after completing CTRX treatment. Stones and sludge, which had not been detected before CTRX administration, appeared in the gallbladder and common bile duct and led to biliary obstruction and acute cholangitis.
View Article and Find Full Text PDFSingapore Med J
November 2017
Department of Paediatrics, National University Health System, Singapore.
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