In this issue of Immunity, Van Braeckel-Budimmir et al. (2017) reveal that the pathogenic response of mice to a Plasmodium berghei infection is dominated by a Vβ8.1 T cell response. Mice lacking Vβ8.1 T cells fail to mount a pathogenic response, thus showing that the TCR locus can be an Immune response (Ir) gene.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870865 | PMC |
| http://dx.doi.org/10.1016/j.immuni.2017.10.018 | DOI Listing |
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