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Platelet-Rich Plasma Resultant Cutaneous Nodules on Scalp.
Indian Dermatol Online J
October 2024
MD Pathology, Consultant Pathologist, Vijaya Diagnostic Center, Visakhapatnam, Andhra Pradesh, India.
Therapeutic Potential of Extracellular Vesicles (Exosomes) Derived From Platelet-Rich Plasma: A Literature Review.
J Cosmet Dermatol
December 2024
School of Pharmacy, BRAC University, Dhaka, Bangladesh.
Background: There are exciting advances in the field of exosomes research as a potential regenerative therapy. Platelet-rich plasma represents an abundant source of exosomes.
Aim: To present evidence on the use of platelet-rich plasma-derived exosomes in dermatology and discuss current technical limitations.
Evaluation of the efficacy of microneedling without and with minoxidil 5% and autologous platelet-rich plasma for androgenetic alopecia in men.
Postepy Dermatol Alergol
October 2024
Department of Dermatology, Medical University of Silesia, Katowice, Poland.
Article Synopsis
- Androgenetic alopecia is the most common type of hair loss in men, affecting not only older individuals but also young adults, and causing psychological issues.
- In the study, 92 men aged 20 to 50 were divided into three groups using different treatments: microneedling alone, microneedling with minoxidil, and platelet-rich plasma (PRP) therapy.
- All groups showed improved hair number and density, but only the PRP group had a significant increase in hair shaft thickness, indicating varying effectiveness of the treatments.
Chemotherapy-Induced Alopecia by Docetaxel: Prevalence, Treatment and Prevention.
Curr Oncol
September 2024
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Docetaxel is a commonly used taxane chemotherapeutic agent in the treatment of a variety of cancers, including breast cancer, ovarian cancer, prostate cancer, non-small cell lung cancer, gastric cancer, and head and neck cancer. Docetaxel exerts its anti-cancer effects through inhibition of the cell cycle and induction of proapoptotic activity. However, docetaxel also impacts rapidly proliferating normal cells in the scalp hair follicles (HFs), rendering the HFs vulnerable to docetaxel-induced cell death and leading to chemotherapy-induced alopecia (CIA).
View Article and Find Full Text PDFThe additive value of platelet-rich plasma to topical Minoxidil in the treatment of androgenetic alopecia: A systematic review and meta-analysis.
PLoS One
August 2024
Department of Dermatology, Zhejiang Provincial Dermatology Hospital, Huzhou, Zhejiang, China.
Article Synopsis
- The study aimed to assess whether platelet-rich plasma (PRP) injections offer any benefits over using just Minoxidil for treating androgenetic alopecia by reviewing randomized controlled trials (RCTs).
- Out of five trials analyzed, three had a high risk of bias, but overall, results indicated improved hair density when PRP was combined with Minoxidil compared to Minoxidil alone at various follow-up times.
- The evidence supporting the effectiveness of PRP plus Minoxidil is considered low quality, with limitations such as the small number of studies and variability in PRP preparation, necessitating more comprehensive research in the future.
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